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1)  memantine
美金刚
1.
Antagonistic effects of memantine on Aβ_(25-35)-induced neurotoxicity;
美金刚对β淀粉样蛋白_(25~35)神经毒性的拮抗作用
2.
Bioequivalence of memantine capsules and tablets in human volunteers;
美金刚胶囊剂与片剂的人体生物等效性
3.
Effect of memantine on NMDAR-2B in hippocampus of vascular dementia rats;
美金刚对血管性痴呆大鼠海马N-甲基-D-天冬氨酸-2B受体的影响
2)  memantine
美金刚胺
1.
Determination of Memantine hydrochloride in rats’plasma by precolumn derivation-HPLC
柱前衍生化HPLC测定大鼠血浆中的盐酸美金刚
2.
The labeling precursor of N2S2-Memantine was synthesized from memantine via reaction with chloroacetyl chloride,followed by condensation with N2S2,and then deblocking protecting group with Hg(OAc)2 and H2S.
美金刚胺为原料,先与氯乙酰氯反应,再与二硫二氮缩合,最后与醋酸汞硫化氢反应脱巯基保护基得到标记前体N-[2-(N-(2-巯基乙基))氨基甲酰甲基]-N-(2-巯基乙基)-3,5-二甲基金刚烷胺基乙酰胺。
3.
Several prodrugs of antidepressant Venlafaxine, antidementia memantine and antitumor hydroxyurea were designed and synthesized in order to enhance up the specific selectivity.
本课题进行了抗抑郁药物文拉法辛,老年痴呆治疗药物美金刚胺及抗脑肿瘤药物羟脲的前体药物制备与评价研究,以期获得提高脑靶向释放的新化合物。
3)  memantine hydrochloride
盐酸美金刚
1.
Study on determination and dissolution of memantine hydrochloride tablets by GC;
气相色谱法测定盐酸美金刚片的含量和溶出度
2.
Pharmacokinetics research of memantine hydrochloride in healthy volunteers
盐酸美金刚在健康人体中的药代动力学研究
3.
Memantine hydrochloride, which is uncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist with middle affinity and can protect neurocyte from overexcitation caused by glutamic acid, is used for moderate and severe AD.
盐酸美金刚对N-甲基-D-天冬氨酸受体具有中等亲和力的非竞争性的拮抗作用,可保护神经细胞免遭过量兴奋性氨基酸的毒性作用,临床用于治疗中重度AD。
4)  memantine hydrochloride
盐酸美金刚胺
1.
Study on Analysis Method of Memantine Hydrochloride Tablets;
盐酸美金刚胺含量分析方法的研究
2.
Comparing to different reaction methods, the method starting from 1,3-dimethyladamantane was certified with the memantine hydrochloride synthesized by bromination ,acetimidolation, hydrolysis and acidation.
通过比较不同的反应路线,确定了以1,3-二甲基金刚烷为原料,经溴代、乙酰氨基化、水解反应最后经酸化得到盐酸美金刚胺。
3.
A HPLC-ELSD method was established for determination of memantine hydrochloride in memantinetablets.
建立了HPLC-ELSD测定美金刚胺片中盐酸美金刚胺的含量。
5)  memantine hydrochloride
盐酸美金刚烷胺
1.
HPLC determination of memantine hydrochloride tablets;
高效液相色谱法测定盐酸美金刚烷胺片的含量
6)  Doughty Beauty
刚美
1.
Doughty Beauty:An Old and Young Aesthetic Category;
“刚美”:一个古老又年轻的美学范畴
2.
It is pointed out that since it obtained the meaning of aesthetic main body gas has showed out a kind of aesthetic tendency canonizing solar and doughty beauty.
“刚美”是张玉能先生近几年提出的一个美学范畴。
补充资料:美金刚
分子式:
CAS号:

性质:又名美金刚胺,盐酸美金刚胺。油状物。折射率1.4941。盐酸盐熔点258℃。抗震颤麻痹药。本品通过释放多巴胺,直接或间接地兴奋多巴胺受体而起作用。用于治疗震颤麻痹综合征。制剂有片剂、针剂、滴剂。

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