1) prodrug
[英]['prəʊ,drʌg] [美]['pro,drʌɡ]
前药
1.
Design, Synthesis, and Primary Evaluation on Curcumin Derivative as Prodrugs of Antitumor;
抗肿瘤前药-姜黄素衍生物的设计合成及初步活性测试
2.
Synthesis and Characterization of Scutellarin PEG Prodrugs;
灯盏乙素聚乙二醇前药的合成与表征
3.
Ester prodrug of scutellarin: synthesis,physicochemical property and degradation;
灯盏乙素酯类前药的合成、理化性质及降解研究
2) Prodrugs
前药
1.
Study on prodrugs of naproxen and their dermal permeability;
萘普生前药及其经皮渗透特征
2.
CONCLUSION:Many natural products may be metabolized in vivo and are called prodrugs.
结论 :许多天然药物以前药形式存在 ,肠道细菌在其代谢中发挥着至关重要的作
3) prodrug
[英]['prəʊ,drʌg] [美]['pro,drʌɡ]
前体药物
1.
Design,synthesis and antitumor activity of ATRA and butyric acid or valproic acid prodrugs;
全反式维甲酸-正丁酸(丙戊酸)前体药物的设计、合成及抗肿瘤活性研究
2.
Preparation of curcumin prodrugs and their anti-tumor activities in vitro;
姜黄素前体药物的合成及其体外抗肿瘤活性研究
3.
Studies on the Stereoselectivity in Transdermal Permeation and Metabolism of Ketoprofen Prodrugs;
酮洛芬前体药物皮肤渗透代谢的立体选择性研究
4) prodrug structural modification
前药改造
1.
Aim To search for compounds for the treatment of cardiovascular diseases through prodrug structural modifications of cyclovirobuxine D, a single efficient composition distilled from Box plant in China, which was used to treat angina and myocardial infarction.
目的通过对植物活性单体———环维黄杨星D的前药改造,以寻求疗效更好、治疗安全范围更宽的心血管药物。
5) premedication
术前药
1.
Objective: To investigate the effectiveness of administration of Penehyclidine Hydrochloride which is selective antagonist on receptor-M as Premedication in abdominal surgery.
方法:选取腹部外科择期手术69例,随机分为3组(每组23例):对照组(Ⅰ组),不应用术前药;阿托品组(Ⅱ组)和长托宁组(Ⅲ组),分别于麻醉诱导前30min肌肉注射阿托品或长托宁0。
6) Premedication
术前用药
1.
Effect of administering Midazolam for a premedication on circulatory system;
咪唑安定术前用药对血压、心率的影响
2.
Safety evaluation of penehyclidine hydrochloride as premedication in patients with coronary heart disease;
盐酸戊乙奎醚作为冠心病患者术前用药的安全性评价
3.
Penehyclidine Hydrochloride as Premedication of Children General Anesthesia:Clinical Observation
盐酸戊乙奎醚用于小儿全麻术前用药的临床观察
补充资料：前药
分子式：
CAS号：
性质：即前体药物。指用化学方法合成原有药物的衍生物，这种衍生物在机体内能转化成原来药物而发挥作用。因此，前体药物又可称为生物可逆性衍生物。前药应具备以下三个条件：（1）根据具有生物活性的药物分子性质，按治疗需要进行化学改造；（2）进入机体后，不论是否需要酶的作用，要保证恢复原来的药物分子；（3）本身不显示生物活性。
CAS号：
性质：即前体药物。指用化学方法合成原有药物的衍生物，这种衍生物在机体内能转化成原来药物而发挥作用。因此，前体药物又可称为生物可逆性衍生物。前药应具备以下三个条件：（1）根据具有生物活性的药物分子性质，按治疗需要进行化学改造；（2）进入机体后，不论是否需要酶的作用，要保证恢复原来的药物分子；（3）本身不显示生物活性。
说明：补充资料仅用于学习参考，请勿用于其它任何用途。
参考词条