Aim To develop a simple and specific high performance liquid chromatographic (HPLC) method, suitable for the pharmacokinetic studies in vivo , to determine the concentrations of 2 amino 6 cyclopropylamino 9 (2,3 dideoxy β D glyceropent 2 enofuranosyl)purine (Cyclo D4G, D4G prodrug) in rat plasma, urine and liver homogenates.

Design, Synthesis, and Primary Evaluation on Curcumin Derivative as Prodrugs of Antitumor;

Synthesis and Characterization of Scutellarin PEG Prodrugs;

Ester prodrug of scutellarin: synthesis,physicochemical property and degradation;

Study on prodrugs of naproxen and their dermal permeability;

CONCLUSION:Many natural products may be metabolized in vivo and are called prodrugs.

Design,synthesis and antitumor activity of ATRA and butyric acid or valproic acid prodrugs;

Preparation of curcumin prodrugs and their anti-tumor activities in vitro;

Studies on the Stereoselectivity in Transdermal Permeation and Metabolism of Ketoprofen Prodrugs;

Aim To search for compounds for the treatment of cardiovascular diseases through prodrug structural modifications of cyclovirobuxine D, a single efficient composition distilled from Box plant in China, which was used to treat angina and myocardial infarction.

Objective: To investigate the effectiveness of administration of Penehyclidine Hydrochloride which is selective antagonist on receptor-M as Premedication in abdominal surgery.