1) 12-brom-13,14-oxifurazan methyl dehydroabietate
12-溴-13,14-脱氢松香酸甲酯氧化呋咱
1.
Synthesis and characterization of 12-brom-13,14-oxifurazan methyl dehydroabietate;
12-溴-13,14-脱氢松香酸甲酯氧化呋咱的合成与表征
2) methyl 12-bromo-13,14-oxofurazan-deisopropyldehydroabietate
12-溴-13,14-氧化呋咱脱异丙基脱氢松香酸甲酯
1.
Starting from dehydroabietic acid, which was purified from disproportionated rosin, three novel heterocycle compounds, methyl 12,13-oxofurazan-deisopropyldehydroabietate, methyl 12,13-furazan- deisopropyldehydroabietate and methyl 12-bromo-13,14-oxofurazan-deisopropyldehydroabietate were syn- thesized through several steps, such as methylation, bromination, nitration and cyclization.
以歧化松香为原料,将其纯化得到脱氢松香酸,然后经甲酯化、溴代、硝化、成环等步骤,合成了三个新型脱氢松香酸甲酯呋咱的衍生物12,13-氧化呋咱脱异丙基脱氢松香酸甲酯、12,13-呋咱脱异丙基脱氢松香酸甲酯、12-溴-13,14-氧化呋咱脱异丙基脱氢松香酸甲酯。
3) methyl 12,13-oxofurazan-deisopropyldehydroabietate
12,13-氧化呋咱脱异丙基脱氢松香酸甲酯
1.
Starting from dehydroabietic acid, which was purified from disproportionated rosin, three novel heterocycle compounds, methyl 12,13-oxofurazan-deisopropyldehydroabietate, methyl 12,13-furazan- deisopropyldehydroabietate and methyl 12-bromo-13,14-oxofurazan-deisopropyldehydroabietate were syn- thesized through several steps, such as methylation, bromination, nitration and cyclization.
以歧化松香为原料,将其纯化得到脱氢松香酸,然后经甲酯化、溴代、硝化、成环等步骤,合成了三个新型脱氢松香酸甲酯呋咱的衍生物12,13-氧化呋咱脱异丙基脱氢松香酸甲酯、12,13-呋咱脱异丙基脱氢松香酸甲酯、12-溴-13,14-氧化呋咱脱异丙基脱氢松香酸甲酯。
4) methyl 7-carbonyl-12,13-oxifurazandehydroabietate
7-羰基-12,13-氧化呋咱脱氢松香酸甲酯
1.
After treating Ⅴ with sodium azide,methyl 7-carbonyl-12,13-oxifurazandehydroabietate (Ⅶ) was obtained by refluxing in toluene.
以歧化松香为原料,将其纯化得到脱氢松香酸,用硫酸二甲酯酯化后,通过12位溴代、7位氧化、13位硝化得到7-羰基-12-溴-13-硝基脱氢松香酸甲酯(Ⅴ),Ⅴ经过与叠氮化钠反应后,在甲苯中回流关环得到7-羰基-12,13-氧化呋咱脱氢松香酸甲酯(Ⅶ),Ⅶ再用三苯基膦脱氧得到7-羰基-12,13-呋咱脱氢松香酸甲酯Ⅷ,这两种产物的产率分别为83%和76%;产物经IR、1HNMR1、3CNMR和MS进行了表征。
5) 13-furazandehydroabietate
13-呋咱脱氢松香酸甲酯
1.
Ⅶ was further converted to methyl 7-carbonyl-12,13-furazandehydroabietate(Ⅷ) through reacting with tri.
以歧化松香为原料,将其纯化得到脱氢松香酸,用硫酸二甲酯酯化后,通过12位溴代、7位氧化、13位硝化得到7-羰基-12-溴-13-硝基脱氢松香酸甲酯(Ⅴ),Ⅴ经过与叠氮化钠反应后,在甲苯中回流关环得到7-羰基-12,13-氧化呋咱脱氢松香酸甲酯(Ⅶ),Ⅶ再用三苯基膦脱氧得到7-羰基-12,13-呋咱脱氢松香酸甲酯Ⅷ,这两种产物的产率分别为83%和76%;产物经IR、1HNMR1、3CNMR和MS进行了表征。
6) 12-bromo-methyl dehydroabietate
12-溴脱氢松香酸甲酯
1.
12-Bromo-dehydroabietic acid and 12-bromo-methyl dehydroabietate were synthesized with three bromide-system methods,the Br2-acetic acid,NBS and Br2-MnO2 system,respectively.
分别以Br2-冰醋酸、溴代丁二酰亚胺(NBS)和Br2-MnO2三种方法合成12-溴脱氢松香酸和12-溴脱氢松香酸甲酯,并对反应的动力学和不同体系的反应用时、产率、选择性以及合成成本等进行探究。
补充资料：溴吩呋酮
分子式：C17H12Br2O3
分子量：暂无
CAS号：3562-84-3
性质：暂无
制备方法：暂无
用途：用于治疗痛风、高尿酸血症。
分子量：暂无
CAS号：3562-84-3
性质：暂无
制备方法：暂无
用途：用于治疗痛风、高尿酸血症。
说明：补充资料仅用于学习参考，请勿用于其它任何用途。
参考词条