Objective To investigate the transgene expression of mesencgymal stem cells(MSCs), which was genetically modified by adenovirus to express cytotoxic T lymphcyte-associated antigen 4 immunogloblin(CTLA4-Ig) and bone morphogenetic protein 2(BMP2), and study the immunosuppressive function of CTLA4Ig on Adv-BMP2 gene transduced MSCs allograft.

Objective To prepare acellular cancellous bone as carrier for bone morphogenetic protein 2(BMP-2), and observe the ectopic osteogenesis.

Effects of bone morphogenetic protein-2 on aggrecan and collagen type Ⅱ in rabbit lumbar intervertebral disc cells;

Methods The BMP-2-derived peptide was devised and synthetized,and PLGA-[ASP-PEG] was modified with polypeptide by methods of physical entrapment and chemical coupling,using 1-ethyl-3-(3- dimethylaminopropyl) carbodiimide (EDC) and N-hydroxysuccinimide (NHS) as cross-linkers.

To investigate osteogenic characteristics of rat bone marrow mesenchymal stem cells(MSCs)co-cultured with osteoblast(OB)indirectlyand effect of bone morphogenetic protein 2(BMP-2)in osteoblastic differentiation of MSCs; 3.

Objective To investigate the transfection efficiency of the recombinant human bone morphogenetic protein-2(hBMP-2) gene in targeted cells by ultrasound-mediated microbubble destruction.

Cloning of human bone morphogenetic protein-2 gene and the construction of its eukaryotic expression vector;

Construction and production of recombinatant adenovirus expressing human bone morphogenetic protein-2;

Effects of Icariin on the Expression of Bone Morphogenetic Protein-2 in Osteoblasts;