Asymmetric transfer hydrogenation of α-iminoketone methyl 5-[(1,1-dimethylethyl)- imino]acetyl-2-hydroxybenzoate (2) using chiral (S,S)-Ru-TsDPEN as catalyst, gave the optical pure β-amino-1-arylethanol derivative methyl 5-[2-[1,1-dimethylethyl]amino]-1-hydroxyethyl]-2-hydroxyben- zoate (3), which was reduced to afford (R)-(-)-salbutamol.

Derivatives of chiral 1,2-diphenyl-2-aminoalcohol were first used to promoting diethylzinc addition to α-ketoimine esters to obtain chiral non-natural α-amino esters(1,4-addition products) in the highest yield of 67% with 44%e.

Direct asymmetric aldol addition of methyl ketones to α-ketoamides was achieved using L-proline as a chiral catalyst.

The Henry reaction of cyclic α-ketoesters and α-ketoamides was achieved using triethylamine as a promoter.

This paper reports a method for preparation of α-ketoamide by using Palladium (Ⅱ) complexes catalyzed double carbonylation reaction of phenyl halide with carbon monoxide in the presence of diethylamine.

Synthesis and crystal structure of the mononuclear nickel compound NiL_2 withα-diimine

Novel poly(imino ketone)(PIK) was synthesized via palladium catalyzed polycondensation reaction.

1,4-Bis-(4-bromobenzoyl)benzene as the monomer of poly(imino ketone) was synthesized by Friedel-Crafts benzoylation reaction.

Novel poly(imino ketone) s (PIKs) as high performance polymers were obtained by the condensation polymerization of 1,4-bis-(4-bromobenzoyl)benzene and aromatic diamines as the monomers via palladium-catalyzed amination reaction.