1) propacetamol hydrochloride
盐酸丙帕他莫
1.
After through acylate,amination,acidification,the propacetamol hydrochloride was obtained.
盐酸丙帕他莫为一种非成瘾性镇痛药。
2.
Objective To establish a HPLC method for the determination of related substances in propacetamol hydrochloride.
目的建立HPLC法测定盐酸丙帕他莫的有关物质。
2) Propacetamol
丙帕他莫
1.
Efficacy and safety of sufentanil with propacetamol for intravenous analgesia after upper abdominal surgery
舒芬太尼复合丙帕他莫用于上腹部手术患者术后静脉镇痛的效果及安全性
3) Embonic acid disodium salt
帕莫酸二钠盐
4) Patamostat
帕莫司他
5) Palmoxiric Acid
帕莫酸
6) camostat mesylate
卡莫他特甲磺酸盐
1.
In the presence of DCC ( N,N ′-dicyclohexylcarbodiimide),Ⅰ reacts at first at room temperature (25 ℃) with N,N -dimethylcarbamoylmethyl p -hydroxyphenylacetate,then the product is purified by changing it to carbonic salt,at last methanesulfonic acid is added to adjust pH to 3 to give camostat mesylate in 64 .
以对氨基苯甲酸为起始原料,水浴加热至50℃,与单氰胺进行反应,然后加入w(HCl)=5%的水溶液使产品析出,一步合成对胍基苯甲酸盐酸盐(收率为76 4%);它与对羟基苯乙酸N,N 二甲基氨基甲酰甲酯在25℃、二环己基碳二亚胺(DCC)存在下酯化缩合,再转化成碳酸盐进行精制,所得产物和水形成的悬浮液用甲磺酸调pH=3,得到卡莫他特甲磺酸盐(总收率为64 4%)。
补充资料：盐酸丙帕他莫
分子式：C14H20N2O3.HCl
分子量：300.78
CAS号：66532-85-2
性质：
分子量：300.78
CAS号：66532-85-2
性质：
说明：补充资料仅用于学习参考，请勿用于其它任何用途。
参考词条