) Nees(30% andrographolide) was used as experimental material,and the model of a second order quadratic equation for supercritical carbon dioxide extracting and crystallizing andrographolide was built by response surface methodology(RSM).

Study on extraction of Nostoc commune vauch polysaccharides by response surface methodology;

Enzymatic Hydrolysis Technology of Grass Carp Protein Based on Response Surface Methodology;

Optimization of Laccase production by White-rot Fungus Y10 in liquid cultures using Response Surface Methodology

The ranges of reaction temperature, reaction time and dialysis time were confirmed through single factor experiment, then a response surface method was conducted to get the following optimal parameters: reaction time 16.

Based on the single factor experiment,the response surface method with three factors at three levels is adopted according to the principle of central compages design.

On basis of single-factor experiments,the optimum conditions for the extraction of theasaponins were obtained through Box-Benhnken Centeral composite designs and Response Surface Methodology(RSM).

Methods:Response surface method(RSM) was applied to a fractional design.

The optimum process parameters of the Parabramis pekinensis enzymatic hydrolysis were determined with Box-Behnken response surface metnodology(RSM).

Fermentation medium of Brevibacterium epidermidis ZJB-07021 producing R-amidase was optimized by using response surface methodology(RSM).

The response surface methodology(RSM) is used to optimize the conditions for the maximum conversion to biodiesel and to understand the significance and interaction of the factors affecting the biodiesel production.