1) Grignard reagent cross-coupling reaction
Grignard试剂偶联反应
2) Grignard reagent
Grignard试剂
1.
Preliminary studies on the addition orientation of 2-dialkylthiomethylene-5, 5-dimethyl-1, 3-cyclohexadione with Grignard reagents;
2-双烷硫基亚甲基-5,5-二甲基-1,3-环己二酮与Grignard试剂加成反应取向的初步研究
2.
On the basis of the one-carbon unit transfer reaction of tetrahydrofolate coenzymes,six cyclohexyl ketone compounds were synthesized successfully with benzimidazolium salt as the tetrahydrofolate coenzyme model at formic acid oxidation level and Grignard reagent as a nucleophile to which one carbon unit was trans.
以2位环己基取代苯并咪唑盐作为甲酸氧化态的四氢叶酸辅酶模型,与亲核Grignard试剂作用,将甲酸氧化态的一碳单元转移给亲核试剂,成功地实现了6类具有潜在应用价值的环己基甲酮的绿色仿生合成,其结构用元素分析、1H NMR、IR和MS等方法进行了表征,并对反应机理和反应条件进行了讨论。
3.
Based on the one-carbon unit transfer reaction of tetrahydrofolate coenzymes,n-pentanal was synthesized successfully by using benzoimidazolium salt as the tetrahydrofolate coenzyme model at the formic acid oxidation level and the Grignard reagent as a nucleophile to which one carbon unit was transferred.
模拟四氢叶酸辅酶一碳单元转移反应,通过其甲酸氧化态模型化合物苯并咪唑盐与一碳单元的受体Grignard试剂的加成-水解反应,为正戊醛的合成提出了一种仿生合成新方法,并对其反应机理和条件进行了讨论。
3) benzaldehyde
[英][ben'zældihaid] [美][bɛn'zældə,haɪd]
Grignard试剂C_6H_5MgBr
1.
Synthesis of benzaldehyde via C_6H_5MgBr;
用Grignard试剂C_6H_5MgBr合成苯甲醛
4) Grignard reagents
Grignard试剂
1.
In this dissertation we studied (Z)-α-silylvinyl Grignard reagents and (E)-α-iodovinylstannanes underwent a cross-coupling reaction in the presence of Pd(PPh_3)_4 catalyst to afford stereoselectively the difunctionalized 1,3-dienes containing silicon ang tin in good yields.
本论文研究了(Z)-α-硅基烯基Grignard试剂在Pd(PPh_3)_4催化下与(E)-α-碘代烯基锡烷的交叉偶联反应，为立体选择合成(Z，Z)-2-硅基-3-锡基-1，3-二烯提供了方便方法。
5) Grignard reaction
Grignard反应
1.
Grignard reaction with long chain alkyl magnesium bro- mide converted the formyl group into the acyl group.
以焦脱镁叶绿酸-a甲酯(1)为起始原料,通过E环保护和3-位乙烯基的氧化反应得到卟吩醛2,与长链烷基溴化镁的Grignard反应将3-位甲酰基转化为1-羟长链烷基,选用TPAP和N-甲基吗啉N-氧化物混合氧化剂对卟吩仲醇3的羟基进行氧化,生成3-位烷酰基焦脱镁叶绿酸-a衍生物4,再与长链烷基溴化镁进行Grignard反应,得到亲核加成产物卟吩叔醇5和还原产物3;以对甲苯磺酸催化,卟吩醇3和5在干燥苯中回流脱水,分别给出反式结构的3-位长链烷基单或者双取代的焦脱镁叶绿酸-a甲酯衍生物6和7。
2.
The carbonyl group on E-ring of methyl pyropheophorbide-d was protected and Grignard reaction with 1-ethylpropyl magnesium bromide was performed.
与Tam iaki等人以W ittig和Knoevenagel反应合成卟吩衍生物的方法不同[6],本文选择焦脱镁叶绿酸-α甲酯(MPP-α)(1)为起始原料,通过氧化和应用范围更广的Grignard反应,在3-位构建新的碳碳。
3.
The very important pharmaceutical intermediate p-fluoro-α-methylstyrene was synthesized using fluorobenzene,bromine and acetone as raw materials via bromination,Grignard reaction and dehydration.
以氟苯、溴和丙酮为原料,通过溴代反应、Grignard反应,再经脱水反应制得医药中间体对氟α-甲基苯乙烯。
6) reactive coupling agent
反应性偶联剂
1.
The strengthening action of the reactive coupling agent accompanied by the co - coupling agent on the second - phase - interface and their t.
根据高密度聚乙烯/碳酸钙(HDPE/CaCO_3)复合体系中各种相界面的特征,把CaCO_3和偶联剂之间通过某种物理化学作用所形成的相界面称之为第1相界面,把偶联剂和HDPE基体之间通过缠绕等作用所形成的相界面称之为第2相界面,考察了反应性偶联剂和助偶联剂对HDPE/CaCO_3复合体系中第2相界面的强化作用及其对复合体系增韧效果的影响。
补充资料：Grignard reagent
通式RMgX（R-烃基，X-卤素）。简称格氏试剂：是由法国V·格林尼亚首先于1901年用卤代烃和镁屑在无水乙醚中反应制得的。格氏试剂是用途极广的有机合成试剂，能与醛、酮、酯、腈、环氧化合物等发生加成反应；能与一些金属卤代物反应生成金属有机化合物。
说明：补充资料仅用于学习参考，请勿用于其它任何用途。
参考词条