By using the helix theory proposed by authors the rotatory direction of molecular can be deduced from configuration and conformation;conversely,the absolute configuration of molecules also can be deduced from the rotatory direction and value for some special biphenyl derivatives and similar compounds.

Study on the quantitative structure-activity relationship of γ-DDB derivatives;

Two compounds were synthesized by introducing the conjugated groups to the distyrylarylene backbone by using Wittig-Horner reactions.

Acute lethal toxicity, the negative logarithm of 12 h acute median lethal molar concentration (expressed as 12h-log1/LC_ 50, mol/L) of a series of benzene derivatives to Rana japonica tadpoles was determined.

Structure-toxicity relationship of 30 mono-substituted benzene derivatives were studied.

0 from Accelrys Company was used to calculate diverse molecular descriptors of 100 data, which are EC50 of photobacterium phosphoreum for benzene derivatives, and QSAR predictive models were built by GFA method using selected descriptors.