1.
It is at this point that extreme despair and frustration are likely to set in.
这个时候，极度的失望和挫败感很有可能将你包围。
2.
Severe disappointment or set-back
（极大的）失望，挫折
3.
In the utter sickness of longing and disappointment, she went home.
他怀着渴望又失望的极度苦痛心情回家了。
4.
Suffering from or exhibiting overwhelming sorrow, grief, or disappointment.
极度伤心的遭受或表现出极度悲痛、哀伤或失望的
5.
The man lost in the desert was desperate for water.
在沙漠中迷失方向的人极度渴望得到水。
6.
Like many people, Diana was immensely disappointed by the failure of her marriage.
如同许多人一般，黛安娜对自己婚姻的失败感到极度失望。
7.
She is in disappointment for his attitude.
她对他的态度感到失望。
8.
a halt in the arms race; a nuclear freeze.
发射的中断使战士们失望至极。
9.
He prayed and supplicated in terms so moving, that even the officer was touched, and, although firm in his duty, he kindly said, "My worthy friend, let me beg of you to calm your apprehensions.
他拼命的求情，他的恳求和眼泪虽毫无用处，但他那极度失望的样子却打动了警长的同情心。
10.
It is a big letdown when I am not accept by harvard university.
当我的入学申请被哈佛大学拒绝时,我失望极了。
11.
It was a big letdown when I wasn't accepted by Harvard University.
"当我的入学申请被哈佛大学拒绝时,我失望极了。"
12.
I was disappointed by the attitude of the banks.
我对银行的态度感到失望。
13.
The hope has the mind the transportation. Has the demeanor not to lose actually humorously.
希望有心灵的交通。有风度却不失幽默。
14.
Andrew had a sense of great sadness and of loss.
安德鲁有一种极度怅惘和失落的感觉。
15.
No longer desperate and pessimistic, he cherished life.
“绝望”没有了，“悲观”消失了，他成了一个热爱生命的积极的人。
16.
Falcon or Hawk- One eager or hot in the pursuit of an object much desired.
鹰或隼－征对某种事物有极度追求渴望的人。
17.
He longed to cast off the exuberance of joy that oppressed him.
他非常希望发泄一下积压在心头的极度欢乐。
18.
In the past decade,human gene therapy aspired great expectations from public.
基因治疗一度红红火火，激起公众极大的期望。