1.
There should be collective leadership in settling major issues.
集体领导解决重大问题；
2.
This was one of the big issues about which the Gang of Four spread utter confusion.
这是被“四人帮”搞乱了的一个重大问题。
3.
Delay in transport of the victims was a significant problem.
受难者在运输中的延误是个重大问题。
4.
Matter of great weight be handle by the general manager himself
重大问题由总经理亲自处理
5.
Matters of great weight are handled by the general manager himself.
重大问题由总经理亲自处理。
6.
The speaker side-stepped some major questions.
演讲者避开了一些重大问题。
7.
The father confronted the children with large questions.
父亲把重大问题摆在子女面前。
8.
They tried to pin him down on major issues.
他们试图说服他就重大问题表明立场。
9.
Philosophic views and significant issues in philosophic research;
哲学观与哲学研究的重大问题(英文)
10.
Ownership is an important theoretical and practical problem.
所有制问题是重大的理论问题及现实问题。
11.
Joan: I am going to put a most solemn question to you.
琼，听我问你一个极为重大的问题。
12.
As for the two great issues of peace and development, the first has not yet been resolved, and the second is even more pressing than before.
和平与发展两大问题，和平问题没有得到解决，发展问题更加严重。
13.
Well, just a little bit. No problem.
超重一丁点儿。不过问题不大。
14.
This is a matter of great significance.
这是一个具有重大意义的问题。
15.
The differences between the two sides involved major matters of principle.
双方的分歧涉及一些重大原则性问题。
16.
We have not always understood the magnitude of your problems.
我们往往不理解你们的问题之重大。
17.
Those facts were influential in solving the problem.
那些事实对解决问题有重大的影响。
18.
a vital, political, topical, etc issue
重大的、 政治的、 时事的...问题