2) γ-glutamyl cysteine synthetase(γ-GCS)
γ-谷氨酰半胱氨酸甘氨酸合成酶
3) Folylpolyglutamate synthetase
叶酰聚谷氨酸合成酶
1.
As one of the key-enzymes in folic acid metabolic pathway, Folylpolyglutamate synthetase (FPGS) content and activity directly associated with the effects of MTX.
背景:氨甲蝶呤(Methotrexate,MTX)是许多叶酸途径抗肿瘤药物的前体,存在L-(+)-MTX和D-(-)-MTX 2种形式的对映体,广泛应用于淋巴瘤、急性白血病和肺癌等多种肿瘤的治疗,作为MTX代谢途径中的关键酶之一的细胞内叶酰聚谷氨酸合成酶(folylpolyglutamate synthetase,FPGS),其含量和活性直接与MTX作用效果相关,已成为当今研究的热点,但有关FPGS定量检测的报道甚少。
4) γ-glutamylcysteine synthetase
γ-谷氨酰半胱氨酸合酶
1.
Objective To explore the mechanism of traditional Chinese medicine(TCM) treatment according to syndrome differentiation in treating chronic obstructive pulmonary disease(COPD) by observing the changes of nuclear factor-κB(NF-κB) and γ-glutamylcysteine synthetase(γ-GCS) expression levels in rats.
目的通过观察慢性阻塞性肺疾病(COPD)大鼠核因子κB和γ-谷氨酰半胱氨酸合酶(γ-GCS)水平的变化,探讨中医药治疗COPD的机理。
2.
Objective To explore the regulation of peroxisome proliferator-activated receptor γ coactivator 1α(PGC-1α) and NF-E2-related factor 2(Nrf2) on expression of γ-glutamylcysteine synthetase(γ-GCS),and their roles in chronic obstructive pulmonary disease(COPD).
目的探讨过氧化物酶体增殖物激活受体γ辅激活因子1α(PGC-1α)和红系衍生的核因子相关因子2(Nrf2)对γ-谷氨酰半胱氨酸合酶(γ-GCS)表达的调控及其在COPD中的作用和意义。
5) γ-glutamylcysteine synthetase
γ-谷氨酰胺半胱氨酸合成酶
1.
The effects of ambroxol hydrochloride on transforming growth factor-β_1 and γ-glutamylcysteine synthetase in lung of smoking rats;
盐酸氨溴索对吸烟大鼠肺内转化生长因子-β_1和γ-谷氨酰胺半胱氨酸合成酶表达的影响
6) γ-glutamylcysteine synthetase
γ-谷氨酰半胱氨酸合成酶
1.
Cloning and Hyperxpression of γ-glutamylcysteine synthetase from Saccharomyce cerevisiae;
酵母γ-谷氨酰半胱氨酸合成酶基因的克隆与原核高效表达
2.
The activity of γ-glutamylcysteine synthetase was showed by the content of inorganic phosphate formed in the re.
方法在体外实验中,以鼠红细胞裂解液为反应体系,分别检测对照组和低、高剂量同型半胱氨酸处理后反应体系中生成的无机磷酸和谷胱甘肽含量,以生成的无机磷酸的mmol数表示γ-谷氨酰半胱氨酸合成酶的活性。
3.
Objective To explore the influence of inhaled glucocorticosteroid on γ-glutamylcysteine synthetase(γ-GCS) in inflammatory cell of sputum in children with asthma.
目的探讨吸入糖皮质激素对哮喘患儿痰炎性细胞γ-谷氨酰半胱氨酸合成酶(γ-GCS)的影响。
补充资料：氨基酰合成酶或氨基酰-tRNA合成酶
氨基酰合成酶或氨基酰-tRNA合成酶
催化一个特定氨基酸与ATP形成AA-AMP，并使AA-AMP与特定的tRNA相结合形成AA-tRNA和游离AMP的酶，已发现20余种。
说明：补充资料仅用于学习参考，请勿用于其它任何用途。
参考词条