Protective mechanism of 2-deoxyglucose in fetal rat′s hypoxic-ischemic cerebral damage mediated by ER stress of intrauterine distress;

Preparation and in vitro release behavior of poly(DL-lactide) microspheres containing 2-deoxyglucose

2-deoxyglucose,carrot juice and tomato juice have great effect on the growth of Phaffia rhodozyma and astaxanthin production.

Objective To investigate the effect of 2-deoxy-D-glucose(2-DG)on the proliferation,cell cycle and apoptosis in osteosarcoma LM8 cells under the normal and hypoxic conditions.

In order to screen high-yield avilamycin-producing strain,a scheme of "random NTG mutation+ glycine and 2-deoxy-D-glucose resistant rational screening" was proposed after investigating the metabolism of glucose and ammonium by Streptomyces viridocbromogenes 96(SV-96).

2-deoxy-D-glucose is a natural monos.

One hour after administration,each mouse was injected intravenously with 14C-2-deoxy-glucose.

In basic condition the cyclopropyl-substituted chlorin 3 was converted into pyropheophorbide 4 by demethoxyformylation.

Methyl pyropheophorbide-d was used as starting material and the Knoevenagel reaction of the aldehyde group on pyropheophorbide with active methylene group in β-diketone, α-cyanoketone or malono- nitrile was carried out to complete the synthesis of derivatives of methyl pyropheophorbide-a substituted with five-membered heterocycle at 3-positipon.