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1)  h-DTD
人源D-酪氨酰tRNA脱酰基酶
1.
Objective To explore the function of human D-Tyr-tRNATyr deacylase(h-DTD)It\'s influence on nonselective cation channels permeability of Na+,K+ and Ca2+ in neuroblastoma SH-SY5Y cell line.
目的探讨人源D-酪氨酰tRNA脱酰基酶(h-DTD)对人神经母细胞瘤细胞SH-SY5Y的非选择性阳离子通道通透性的影响。
2)  tyrosyl-tRNA synthetase
酪氨酰-tRNA合成酶
1.
Mutations in tyrosyl-tRNA synthetase, glycyl-tRNA synthetase and alanyl-tRNA synthetase from patients and mice models were identified to cause two subtypes of Charcot-Marie-Tooth disease and cerebellar Purkinje cell loss, respectively.
近期在对一些患有神经退行性疾病的病人和小鼠模型的研究中发现,位于酪氨酰-tRNA合成酶、甘氨酰-tRNA合成酶和丙氨酰-tRNA合成酶上的突变,可分别导致DI腓骨肌萎缩症(Charcot-Marie-Toothdisease,CMT)C型,腓骨肌萎缩症2D型及小脑浦肯雅(Purkinje)细胞丢失。
3)  aminoacyl-tRNA synthetase
氨基酰-tRNA合成酶
1.
Physiology,pathology and drug design related with editing of aminoacyl-tRNA synthetase;
氨基酰-tRNA合成酶编校相关的生理、病理效应和药物设计
2.
Recent studies show that aminoacyl-tRNA synthetases play important roles in cell life,such as taking part in intracellular RNA degrading,mRNA splicing,gene transcription regulation,immune response and angiogenesis.
氨基酰-tRNA合成酶(ARS)催化特异的氨基酸结合到对应tRNA上,确保mRNA高精度地翻译为蛋白质。
3.
Recent studies showed that some mitochondrial aminoacyl-tRNA synthetases are closely related with human diseases.
氨基酰-tRNA合成酶是一类古老的蛋白质,催化蛋白质生物合成中的第一步反应。
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4)  aminoacyl tRNA synthetase
氨基酰tRNA合成酶
5)  methionyl-tRNA transformylase
甲硫氨酰tRNA转甲酰基酶
6)  human tryptophanyl-tRNA synthetase
人色氨酰tRNA合成酶
1.
In vitro transcripts of these mutant genes were tryptophanylated by Bacillus subtilis and human tryptophanyl-tRNA synthetases(TrpRS),and the kinetic parameters were determined.
subtilis)和人色氨酰tRNA合成酶(TrpRS)进行氨酰化反应,并测定动力学常数。
补充资料：氨酰-tRNA合成酶
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CAS号：

性质：按照下列反应催化氨基酸与特定tRNA相结合的酶。氨基酸+tRNA+ATP→氨酰-tRNA+AMP+ppi这个反应分两步进行。第一步：氨基酸+ATP+酶=酶·氨基酸·cAMP+ppi随后氨酰基转移到tRNA的3′-端腺苷酸残基上。酶·氨基酸·cAMP+ tRNA=氨酰-tRNA+酶+AMP这些合成酶也催化氨酰- tRNA的脱酰作用：氨基- tRNA=氨基酸+ tRNA

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