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1)  amino pyrimidine compounds
氨基嘧啶类化合物
1.
Based on B3LYP/6-311G* of DFT,the geometries of amino pyrimidine compounds were optimized,and then their visible absorption maxima were calculated with TD-DFT method and ZINDO/S method respectively.
对几种氨基嘧啶类化合物利用密度泛函的B3LYP/6-311G*进行构型优化,然后用TD-DFT方法和ZINDO/S方法分别计算了它们的最高吸收波长,结果与实验值较好吻合。
2)  pyrimidinamine compound
嘧啶胺类化合物
3)  Pyrimidines
嘧啶类化合物
1.
An HPLC method for determination of five pyrimidines,such as 5-fluorouracil,5-bromouracil,5-iodouracil,sulfadiazine and sulfamethazine on diallyl trisulfide-bonded stationary phase(DTSP) was first developed by HPLC.
研究发现,大蒜新素固定相能较好地分离上述五种嘧啶类化合物,并用于模拟人尿液样品的定量分析。
4)  pyridopyrimidine
吡啶并嘧啶类化合物
1.
Recent advances in the synthesis of pyridopyrimidine analogues were reviewed in this article in- cluding pyrido[2,3-d]pyrimidine, pyrido[1,2-a]pyrimidine and pyrido[4,3-d]pyrimidine analogues with 71 references.
综述了近二十年来吡啶并嘧啶类化合物的合成研究进展,介绍了三大类吡啶并嘧啶类化合物的主要结构类型:吡啶并[2,3-d]嘧啶类化合物、吡啶并[1,2-a]嘧啶类化合物、吡啶并[4,3-d]嘧啶类化合物的相关合成方法及新进展。
5)  2-(4,6-dimethoxy-pyrimidin-2-yloxy)-N-het/aryl-benzylamine derivatives
2-嘧啶氧基-N-芳基苄胺类化合物
1.
According to the result of biological experiments,2-(4,6-dimethoxy-pyrimidin-2-yloxy)-N-het/aryl-benzylamine derivatives were found to have the inhibiting activity of acetolactate synthase(ALS),and the relationship between these compounds and their activity was studied by 3D-QSAR:CoMFA and CoM-SIA.
生物活性测试结果表明,2-嘧啶氧基-N-芳基苄胺类化合物对ALS具有一定的抑制活性。
6)  6-(phenylthio) thymine HEPT analogues
6-苯硫基胸腺嘧啶类化合物
补充资料:氨基嘧啶
分子式:
CAS号:

性质:常见的如下。2-氨基嘧啶,针状结晶,熔点127~128℃,溶于水,盐酸盐熔点196℃,苦味酸盐熔点237~238℃。4-氨基嘧啶,片状结晶,熔点151~152℃,溶于水与乙醇。5-氨基嘧啶,熔点171~172℃。氨基处于嘧啶环的2位,4位,6位时,均可以亚氨基形式构成互变异构体。由相应的氯代嘧啶与氨反应制取。用作合成各种药物的中间体。

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