1) serotonin 5-HT4 receptor isoforms
5-HT4受体亚型
1.
Objective:To investigate the mRNA expression of four serotonin 5-HT4 receptor isoforms(5-HT4Ra,5-HT4Rb,5-HT4Rg, 5-HT4Ri) in interatrial septum with atrial fibrillation(AF) and study its clinic significance.
术中取房间隔组织,采用SYBRGreen实时荧光定量PCR检测各组中5-HT4受体亚型mRNA的表达。
2) 5-HT4 receptor
5-HT4受体
1.
Objective To investigate the effect of 5-hydroxytryptamine(5-HT) and the plasticity of 5-HT3 and 5-HT4 receptors in the myenteric plexus on the pathogenesis of irritable bowel syndrome(IBS) subgroups.
目的探讨5羟色胺(5-HT)以及5-HT3、5-HT4受体可塑性在肠易激综合征(IBS)不同亚型发病中的作用。
2.
In addition,the stimulation of 5-HT4 receptors elicits gastrointestinal contractile activity and increases the rate of gastric emptying in humans and dogs.
而刺激5-HT4受体会引起人和犬的胃肠收缩动作并提高胃排空率。
3.
Aim To investigate the pharmacological effects of 5-HT4 receptor agonist SHR116958 on its prokinetic activity with in vivo and in vitro animal models.
目的通过3种小鼠整体和离体豚鼠回肠模型,研究新5-HT4受体激动剂SHR116958促进胃肠蠕动的作用。
3) 5-HT4 receptor partial agonist
5-HT4受体激动剂
4) 5-HT4 antagonist
5-HT4受体拮抗剂
5) 5-HT1A receptor subtype
5-HT1A受体亚型
1.
In order to investigate the mechanisms of 5-HT1A receptor subtype in the sensory modulation,double immunofluoresence histochemistry was used to observe the coexistence of 5-HT1A receptor subtype with substance P(SP),vesicular glutamate transporter I(VGLUT1)and galanin(Gal)in the rat dorsal root ganglion(DRG)neurons.
为探讨5-HT1A受体亚型参与感觉信息调控的机制,本文利用免疫荧光组织化学双重染色技术观察了该受体亚型与P物质(SP)、I型囊泡膜谷氨酸转运体(VGLUT1)和甘丙肽(Gal)在大鼠背根神经节(DRG)神经元内的共存状况。
6) 5-HT_1 receptor subtype
5-HT1受体亚型
1.
To investigate the involvement of 5-HT_1 receptor subtypes in the transmission and modulation of the neuropathic pain, the expression of 5-HT_ 1A, 5-HT_ 1B, 5-HT_ 1D, 5-HT_ 1E and 5-HT_ 1F receptor subtype mRNAs in the spinal dorsal horn of the rat with spared nerve injury (SNI) was detected by reverse transcriptase-polymerase chain reaction (RT-PCR) technique.
为探讨脊髓内5-HT1受体亚型在神经病理性痛信息传递和调控中的作用,本研究利用反转录聚合酶链式反应(RT-PCR)技术观察了坐骨神经分支选择性损伤(SNI)模型大鼠脊髓背角内5-HT1A、5-HT1B、5-HT1D、5-HT1E和5-HT1F受体亚型mR-NAs表达变化。
补充资料：5-[4-{2-(5-ethyl-2-pyridyl)ethoxy}benzylidene]
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说明：补充资料仅用于学习参考，请勿用于其它任何用途。
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