Prevalence of Vascular Cognitive Impairments and the Change of Cognitive Condition in 4 Years;

Comparative analysis between leukoaraiosis subjects with and without cognitive impairment;

Both diabetes mellitus and cognitive impairment are frequent disorders in elderly people.

Neuropsychological tests will be used to measure some of these patients in order to learn whether patients with TD have cognitive impairment.

To negative and positive symptoms, the results of some studies are that cognitive deficits are relate to negative symptoms, some results are that cognitive deficits are relate to positive symptoms, the other results are that cognitive dificits are relate to both negative and positive symptoms.

Objective Cerebral infarction is one of common diseases which threatens severely healthy of human especial middle-old people, patients often are left behind different degree cognitive function impairment, which not only affect quality of life and social adaptation ability of patients, but also bring patient, family and society great psychic pain and heavy economic burden.

That endogenous NGF and BDNF can increase the activity of cholinergic system of the basal forebrain and the plasticity of neuron of hippocampus is thought to contribute to the improvement of cognitive function impairment.

With the development of imaging technology and clinical research of cerebrovascular disease,some progress has been made in vasogenic cognitive impairment.

Objective⑴Selecting the patients with Lacunar Infarction (LI) and LI CognitiveImpairment, contrast researches are studied with the characters anddistributing features of the Traditional Chinese Medicine (TCM)syndromes of the LI and LI Cognitive Impairment.