1) excision repair cross-complementing 1(ERCC1)
核苷酸切除修复交叉互补基因1(ERCC1)
2) ERCC1
核苷酸切除修复交叉互补基因-1
1.
Expression of ERCC1 in colorectal cancer and its clinical significance;
核苷酸切除修复交叉互补基因-1在结直肠癌中的表达及其意义
3) excision repair cross completion gene 1
切除修复交叉互补基因1(ERCC1)
4) Excision repair cross-completion 1 gene
核苷酸酸切除修复交叉互补基因
5) excision repair cross-complementation group 1/ genetics
切除修复交叉互补基因1/遗传学
6) ERCC1
切除修复交叉互补基因1
1.
Objective: To study the relation between expression of excision repair cross- complementing gene 1 (ERCC1) in tissue of non-small cell lung cancer and long-term effect of platinum-based chemotherapy.
目的:研究探讨非小细胞肺癌(non-small cell lung cancer,NSCLC)组织中DNA切除修复交叉互补基因1(excision repair cross-complementing 1,ERCC1)的表达与铂类化疗远期疗效之间的关系,并观察该指标及相关临床因素对患者预后的影响。
2.
A number of nucleic acid repair genes such as excision repair cross-complementing gene 1(ERCC1) and human xeroderma pigmentosum gene D(XPD/ERCC2),the level descent may be susceptible factors to one or certain kinds of tumors;but if these genes′ level are higher,the ability to repair damage and chemotherapy-induced genetic damage will be enhanced,it may be resistance to chemotherapeutic drugs.
一些核酸修复基因,如切除修复交叉互补基因1(ERCC1)及人类着色性干皮病基因D(XPD/ERCC2)的水平下降,可能会成为某种或某几种肿瘤的易感因素;但如果此种基因的水平较高,修复损伤的能力提高,对化疗药物所致基因损伤的修复能力也就增强了,那么可能对化疗药物产生耐药现象。
补充资料：基因内互补
基因内互补
intragenic complementation
指带有处于反式(即相斥）状态的两个拟等位基因的个体呈现接近正常表型的现象。可能是由于两个突变基因所产生的失活产物结合而成为具有活性的蛋白质的结果。如果将两个有关的同质结合子的抽提物混合时可以看到互补现象，叫离体互补。
说明：补充资料仅用于学习参考，请勿用于其它任何用途。
参考词条