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1)  global conformational transition
全局构象变化
1.
The effects of antagonist on the conformational transition and global conformational transition pathway of calmodulin(CaM) are investigated by means of two different conformations of open and closed states.
根据已发现的钙调蛋白(CaM)打开和闭合两种不同的构象,研究了拮抗剂对构象变化的影响以及CaM全局构象变化路径。
2)  global change
全局变化
3)  Conformation change
构象变化
4)  conformational change
构象变化
1.
The pH induced conformational change of the binary anionic monomers and acrylamide terpolymer(P3A) composed of the non ionic monomer acrylamide(AM), strong acidic monomer 2 acrylamide 2 methylpropane sulfonate(AMPS) and weak acidic monomer(AA) were studied in dilute aqueous solution by viscosimetry and spectrometry.
采用粘度和光谱方法 ,研究了强酸性和弱酸性 2种阴离子型单体与丙烯酰胺的三元共聚物(P3A)在稀水溶液中 pH诱发的构象变化 ,P3A聚合物由丙烯酰胺 (AM)和强酸性离子单体 (AMPS)及弱酸性离子单体 (AA)组成 。
2.
A chromatographic method used to study the conformational changes of proteins is proposed.
通过比较6种天然和变性蛋白的色谱行为,提出在不含盐酸胍的非变性体系中利用尺寸排阻色谱法研究蛋白质的构象变化。
3.
The results showed that the increase of the concentration of oxidized DTT leads to the losing of the activity of CK,as well as the conformational change.
肌酸激酶起初微小的结构变化就会导致酶活性的迅速丧失,而且其的失活先于明显可测的整体构象变化,酶分子的活性部位处于柔性区域内。
5)  Conformational changes
构象变化
1.
The protein structural transitions that occur in the pathway are at the heart of the specific conformational changes that form the individual intermediates involved in the rate-limited pathways that can distinguish one pathway from another.
研究蛋白质去折叠路径及其在外扰下的构象变化,对揭示其折叠途径和机理至关重要。
6)  local conformation
局部构象
1.
According to the thorough analysis about biologic features of TFBSs,a new prediction algorithm integrating conserved motifs and local conformational knowledge is proposed.
通过深入分析结合位点的生物特征,提出了一种综合利用序列保守模体和局部构象信息的结合位点预测方法,以极大相关得分矩阵作为保守模体的描述模型,并根据二苷参数模型计算位点序列的局部构象,将两类信息得分组合为多维特征向量,在二次判别分析的框架下进行训练和滑动预测。
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