This paper reviews advances in organotin complexes with their antitumor activity in recent years,especially two kinds of new organotin,ionic organotin compound and organotin carboxylate compound,and we also look forward their future development.

In this dissertation, under microwave irradiation, one-step synthesis of imide by using anhydrides with amines was studied,and microwave-promoted synthesis of series of organotin carboxylates by reaction of anhydride, dicarboxylic acid and N,N-tetrafluoro (chloro)-phthaloyl-α-amino acids with organotin oxide or hydroxide was also discussed.

This paper has reviewed some kinds of organotin carboxylates synthesis and application in organicsynthesis.

Organotin carboxylates have attracted considerable attention due to their wide applications in many fields, for example as pesticidal, bactericidal and antitumor agents.