1) 6,7-dihydro-5H-1-pyrindine
6,7-二氢-5H-1-氮茚
1.
3-(2-Oxocyclopentyl)-propanenitrile was synthesized from methyl 1-(2-cyanoethyl)-2-oxocyclopentane-carboxylate by hydrolysis which was converted to the target molecule,6,7-dihydro-5H-1-pyrindine,directly by reductive cyclization and aromatization in one step in the presence of Ni-Cu/γ-Al2O3.
0%;将脱羧产物通入装有Ni-Cu/γ-Al2O3催化剂的固定床反应器中,催化环合最终得到6,7-二氢-5H-1-氮茚,反应总收率33。
3) Nadifloxacin
(±)-9-氟-6,7-二氢-8-(4-羟基-1-哌啶)-5-甲基-1-氧代-1H,5H-苯并喹嗪-2-甲酸
4) 9-Fluoro-6,7-dihydro-5-methyl-1-oxo-1H,5H-benzo[ij]quinolizine-2-carboxylic acid
9-氟-6,7-二氢-5-甲基-1-氧代-1H,5H-苯并(ij)喹嗪-2-羧酸
5) 6,7-Dihydro-5-methyl-5H- cyclopentapyrazine
6,7-二氢-5-甲基-5H-环戊二烯并吡嗪
6) 6,7-dihydro-5H-cyclopenteno[b]pyridine
6,7-二氢-5H-环戊烯并[b]吡啶
1.
6,7-Dihydro-5H-cyclopenteno[b]pyridine was prepared from 1-amino-2-cyanocyclopentene by acetylation, cyclization and chlorination to give 4-amino-2-chloro-6,7-dihydro-5H-cyclopenteno[b]pyridine, which was subjected to Sandmeyer bromination and then catalytic hydrogenated dehalogenation with an overall yield of about 61%.
1-氨基-2-氰基环戊烯经乙酰化、闭环和氯化反应制得4-氨基-2-氯-6,7-二氢-5H-环戊烯并[b]吡啶,再经Sandmeyer溴化和钯炭催化氢化脱卤制得6,7-二氢-5H-环戊烯并[b]吡啶,总收率为61%。
补充资料：[3-(aminosulfonyl)-4-chloro-N-(2.3-dihydro-2-methyl-1H-indol-1-yl)benzamide]
分子式：C16H16ClN3O3S
分子量：365.5
CAS号：26807-65-8
性质：暂无
制备方法：暂无
用途：用于轻、中度原发性高血压。
分子量：365.5
CAS号：26807-65-8
性质：暂无
制备方法：暂无
用途：用于轻、中度原发性高血压。
说明：补充资料仅用于学习参考，请勿用于其它任何用途。
参考词条