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1)  Compound Ipratropium Bromide Solution for Inhalation
异丙托溴铵/沙丁胺醇
2)  Ipratropine
异丙托溴铵
1.
Patients in the experimental group were given Seretide 50μg/ 250μg inhalation,twice daily;and the control group received the inhalation of Ipratropine 50μg,twice per day,and the Salbutamol aerosol was used once in need,6 months for one treatment cycle.
方法将32例COPD病人随机分为两组,实验组给予舒利迭50μg/250μg,每次1吸,每日2次治疗;对照组给予吸入异丙托溴铵50μg,每日2次,并按需使用沙丁胺醇气雾剂治疗,疗程为6个月,在试验前后分别测定肺功能,并比较开始试验前、后6个月两组COPD患者急性发作次数。
2.
Objective To observe the therapeutic effect of atomize inhaling glucocorticoid,terbutaline and beclomethasone ipratropine for pedo-bron-chiolitis and explore the prognostic influence of glucocorticoid.
目的观察糖皮质激素联合异丙托溴铵、特布他林雾化吸入治疗毛细支气管炎的疗效,探讨不同疗程吸入糖皮质激素对毛细支气管炎预后的影响。
3)  Ipratropium bromide
异丙托溴铵
1.
Inhalation of ipratropium bromide combined with terbutaline in treatment of stable chronic obstructive pulmonary disease;
异丙托溴铵和特布他林联合治疗慢性阻塞性肺疾病稳定期的疗效
2.
Fenoterol and ipratropium bromide inhalation alone or combined in treatment of childhood acute paroxysm of asthma;
非诺特罗及异丙托溴铵单用或联用吸入治疗小儿哮喘发作
3.
OBJECTIVE To study the effects of ipratropium bromide and salbutamol on large conductance calcium activated potassium (BK Ca ) channel in trachea smooth muscle cell (TSMC) from guinea pig with asthma.
目的 研究异丙托溴铵和沙丁胺醇对哮喘豚鼠气管平滑肌细胞大电导钙激活钾通道 [largeconductancecalciumactivatedpotassium (BKCa)channel]的作用。
4)  Ipratropium
异丙托溴铵
1.
Objective:To study the efficacy and safety of Tiotropium Inhalation Capsules and Ipratropium metered dose in-haler in patient with moderate-severe chronic obstructive pulmonary disease.
目的:研究噻托溴铵干粉制剂及异丙托溴铵气雾制剂联合舒利迭治疗中重度COPD患者的疗效及安全性。
2.
Ipratropium is effective in decreasing the levels of LTB4 and 15-HETE in lung tissue of COPD rats,and attenuating inflammatory changes of airways.
目的:探讨慢性阻塞性肺疾病(Chronic obstructive pulmonarydisease,COPD)大鼠模型肺组织中白三烯B4(Leukofriene B4,LTB4)与15-羟化二十碳四烯酸(15-hydroxyeicosatetraenoic acid,15-HETE)含量的变化以及异丙托溴铵对其的影响。
5)  Ipratropine
异丙托溴胺
1.
Objective It is to explore the efficacy of combination of β_2 receptor agonist(Salbutamol) and M receptor blocker(Ipratropine) and either agent alone on patients with chronic obstructive pulmonary disease(COPD).
目的探讨慢性阻塞性肺疾病(COPD)患者单纯吸入β2受体激动剂(沙丁胺醇)、M受体阻滞剂(异丙托溴胺)及二者联合应用(可必特)的疗效。
2.
Applying Ipratropine compound in treatment of children with asthmatiform disorders via nebulizer;
前者如异丙托溴胺能有效松弛支气管平滑肌以发挥解痉作用,后者如沙丁胺醇具有高选择性作用,作用维持时间长,给药途径多,为哮喘急性发作首选的对症治疗支气管弛张药。
6)  ipratropium bromide compound
复方异丙托溴胺
补充资料:溴苄铵托西酸盐
分子式:C18H24BrNO3S
分子量:414.37
CAS号:61-75-6

性质:白色结晶性粉末。熔点97-99℃。极易溶于水、醇、丙酮,不溶于苯、醚、乙酸乙酯、己烷。

制备方法:以邻甲苯胺为原料,经重氮化脱氮并用溴置换生成邻溴甲苯,在光照下和溴素溴化生成邻溴苄基溴甲烷,再用二甲胺在压力下胺化得邻溴苄基二甲胺,最后与对-甲基磺酸乙酯加成得成品。

用途:该品为一种肾上腺素阻滞剂。以提高心室致颤阈,故可防治心室颤动,并能直接加强心肌收缩力,改善房室传导作用,用于各种病因所致的室性心律失常,如频发性早搏、阵发性室性心动过速、心室扑动和颤动,尤其对锑剂所致阿-斯氏综合症效果较好。此外,对由于电解质紊乱、酸碱失去平衡或由于洋地黄、奎尼丁等药物中毒所引起的心律失常,也有一定的疗效。为抗心律失常的较好药物。该品有毒。小鼠口服LD50400mg/kg;大鼠肌内注射LD50为250mg/kg。对

说明:补充资料仅用于学习参考,请勿用于其它任何用途。
参考词条