2) 3,4-dihydropyri midin-2(1H)-(thio)ones
3,4-二氢嘧啶-2-(1H)(硫)酮
4) 3,4-dihydropyrimidin-2(1H)-one
3,4-二氢嘧啶-2(1H)-酮
1.
In 1893, Biginelli reported the first synthesis of 3,4-dihydropyrimidin-2(1H)-ones (DHPM) by a very simple one-pot condensation reaction of an aromatic aldehyde, urea and ethyl acetoacetate.
1893年,意大利化学家Biginelli首次利用芳香醛、乙酰乙酸乙酯和尿素三组分"一锅煮法"合成了3,4-二氢嘧啶-2(1H)-酮。
2.
The 5-ethoxycarbonyl-4-phenyl-3,4-dihydropyrimidin-2(1H)-one was synthesized by one-step cyclocondensation of aldehyde,ethyl acetoacetate and urea using four kinds of solid acids as catalysts which are cheap but harmless to environment.
选取价廉、易得且对环境无污染的4种固体酸为催化剂,以苯甲醛、乙酰乙酸乙酯与脲进行环化缩合,一步合成了6-甲基-4-苯基-5-乙氧羰基-3,4-二氢嘧啶-2(1H)-酮。
5) 3,4-dihydropyrimidin-2(1H)-one
3,4-二氢嘧啶-2-酮
1.
One-pot synthesis of 3,4-dihydropyrimidin-2(1H)-one derivatives catalyzed by boric acid;
硼酸催化的一锅法合成3,4-二氢嘧啶-2-酮衍生物
2.
Synthesis of 3,4-dihydropyrimidin-2(1H)-one catalyzed by HClO_4;
HClO_4催化合成3,4-二氢嘧啶-2-酮
3.
One-pot synthesis of 3,4-dihydropyrimidin-2(1H)-ones catalyzed by n-Bu_2SnO;
n-Bu_2SnO催化一锅法合成3,4-二氢嘧啶-2-酮
6) 3,4-dihydropyrimidine-2-ones
3,4-二氢嘧啶-2-酮
1.
The results indicated that the yields of the 3,4-dihydropyrimidine-2-ones were up to 85 %~95 % with the microwave irradiation power 280 W,irradiation time 5 min,mole ratios n(aldehyde) ∶n(β-keto ester) ∶n(urea) =1.
在微波辐射及无溶剂的条件下,氯化镉催化芳香醛、β-酮酸酯和尿素发生Biginelli缩合反应合成了系列3,4-二氢嘧啶-2-酮类化合物。
补充资料：[3-(aminosulfonyl)-4-chloro-N-(2.3-dihydro-2-methyl-1H-indol-1-yl)benzamide]
分子式：C16H16ClN3O3S
分子量：365.5
CAS号：26807-65-8
性质：暂无
制备方法：暂无
用途：用于轻、中度原发性高血压。
分子量：365.5
CAS号：26807-65-8
性质：暂无
制备方法：暂无
用途：用于轻、中度原发性高血压。
说明：补充资料仅用于学习参考，请勿用于其它任何用途。
参考词条