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1)  insulin-producing cells
胰岛素产生细胞
1.
Mesenchymal stem cells trans-differentiate to insulin-producing cells upon microenvironment manipulation in vitro
人工模拟胰腺微环境诱导骨髓间充质干细胞分化为胰岛素产生细胞
2)  insulin-producing cell clusters
胰岛素生成细胞团
1.
Differentiation of mouse embryonic stem cells into insulin-producing cell clusters induced by various growth factors;
多种生长因子诱导小鼠胚胎干细胞分化为胰岛素生成细胞团
3)  Pancreatic Islet Cells Insulin Resistance
胰岛细胞胰岛素抵抗
4)  islet function/insμlin secreation
胰岛细胞功能/胰岛素
5)  Insulin resistance of β cell
胰岛β细胞胰岛素抵抗
1.
Insulin resistance of β cell make insulin resistance and islet β cell dysfunction to connect in islet cellular level,InsR、IRS-1/-2 in the signal transduction is correlated closely with β cell function,which may be relative to the high free fatty acids,oxidative stress,and inflammatory response.
研究证实,胰岛β细胞同外周组织一样存在胰岛素抵抗,即胰岛β细胞胰岛素抵抗。
6)  insulin-producing cells
胰岛素分泌细胞
1.
Role of pancreatic duodenal homeobox gene-1 in committed-differentiation of bone marrow mesenchymal stem cells into insulin-producing cells;
胰腺十二指肠同源框1基因在大鼠骨髓间充质干细胞向胰岛素分泌细胞定向分化过程中的作用
2.
The obstacles in the conversion of proinsulin to insulin in stem cell-derived insulin-producing cells
干细胞源胰岛素分泌细胞中胰岛素原转化障碍的原因及对策
3.
Many reports have obtained insulin-producing cells from ESCs using different strategies,however,these all have various limitations and there is lack of an optimal protocol produ.
将人胚胎干细胞(human embryonicstem cell,hESCs)诱导为胰岛素分泌细胞,成为β细胞替代物的新资源,为解决细胞来源匮乏带来了希望。
补充资料:胰岛


胰岛
islets of pancreas

  胰腺的内分泌部分,是分散在胰腺中的不规则的细胞群。胰岛至少有三种细胞:A(或α2)细胞分泌胰高血糖素;B(或β)细胞分泌胰岛素;近来又发现一种细胞,称为D(或δ或α1)细胞,它在正常情况下分泌生长激素释放抑制激素。D细胞增生或发生肿瘤时,分泌大量胃泌素,称为胃泌素瘤。可引起胃酸分泌过多的消化性溃疡。胰岛这些细胞紧靠在毛细血管上,所分泌的激素,通过毛细血管壁渗入血液内,有调节糖代谢的作用。
  
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