1) farnesoid X receptor gene
法尼醇受体基因
2) Farnesoid X receptor
法尼醇受体
1.
Objective: To explore the mechanism of Farnesoid X receptor(FXR) in ICP enterohepatic circulation by detecting the expression of farnesoid X receptor(FXR) and IBABP in ileum from SD rat model of ICP induced by estradiol benzoate(EB).
目的:通过苯甲酸雌二醇诱导建立孕鼠妊娠期肝内胆汁淤积症(intrahepatic cholestasis ofpregnancy,ICP)模型,检测法尼醇受体(farnesoid X receptor,FXR)、回肠胆汁酸结合蛋白(IBABP)在回肠上的表达,从胆汁酸肠肝循环角度探讨FXR通过IBABP在ICP中的作用机制。
2.
Objective To investigate the expressions of farnesoid X receptor(FXR)and its target gene cholesterol-7α-hydroxylase(CYP7A1)in liver of pregnant rats with intrahepatic cholestasis,and to explore the mechanism of intrahepatic cholestasis of pregnancy(ICP).
目的分析法尼醇受体(FXR)及其靶基因胆固醇7α-羟化酶(CYP7A1)在妊娠期肝内胆汁淤积症(intrahe-patic cholestasis of pregnancy,ICP)孕鼠肝脏的表达情况,探讨FXR与CYP7A1在ICP发病机制中的作用。
3.
Objective: To explore the mechanism of FXR in ICP enterohepatic circulation by building the rat model of intrahepatic cholestasis of pregnancy(ICP) induced by estradiol benzoate(EB) and detecting the expression of farnesoid X receptor(FXR) and IBABP (protein and mRNA) in ileum.
目的:本研究通过建立孕鼠妊娠期肝内胆汁淤积症模型,检测法尼醇受体(Farnesoid X receptor,FXR)、回肠胆汁酸结合蛋白(IBABP)在回肠上的表达,从胆汁酸肠肝循环角度探讨FXR通过IBABP在妊娠期肝内胆汁淤积症中的作用机制,从而明确FXR在回肠胆汁酸转运的作用机制。
3) Farnesoid X Receptor
类法尼醇X受体
1.
Down-regulation of Monocyte Chemoattractant Protein-1 Expression by Farnesoid X Receptor;
类法尼醇X受体下调单核细胞趋化蛋白-1表达的研究
2.
Objective:To investigate the changes of cholesterol 7alpha-hydroxylase(CYP7A1),farnesoid X receptor(FXR),and small heterodimer partner(SHP) expression in liver tissues of bile duct ligated(BDL) rats,and to analyze the relationship between their expression.
目的:通过建立梗阻性黄疸动物模型,观察胆固醇7α-羟化酶(cholesterol 7alpha-hydroxylase,CYP7A1)、类法尼醇X受体(farnesoid Xreceptor,FXR)及小异源二聚体伴侣受体(small heterodi mer partner,SHP)的表达变化,并分析CYP7A1和FXR、SHP之间的关系。
4) farnesoid X receptor
法尼醇X受体
1.
AIM To compare the effects of the potent endogenous farnesoid X receptor(FXR)ligand—chenodeoxycholic acid(CDCA)with ursodeoxycholic acid(UDCA)on biochemical index,hepatic histology, and fatal prognosis in rats with intrahepatic cholestasis of pregnancy(ICP).
目的以熊去氧胆酸(UDCA)为对比,研究法尼醇X受体(FXR)激动剂——鹅去氧胆酸(CDCA)对妊娠期肝内胆汁淤积(ICP)孕鼠血生化指标、肝脏病理及胎鼠预后的影响。
2.
OBJECTIVE: To compare the effect and investigate the mechanism of potent farnesoid X receptor (FXR) ligand-chenodeoxycholic acid(CDCA) with ursodeoxycholic acid(UDCA) on metabolism of bile acid in rats with estrogen-induced intrahepatic cholestasis of pregnancy(ICP).
目的:以熊去氧胆酸(UDCA)为对比,研究法尼醇X受体(FXR)强激动剂——鹅去氧胆酸(CDCA)对妊娠期肝内胆汁淤积(ICP)大鼠胆汁酸代谢的影响及其分子机制。
5) Famesoid X receptor
法尼酯受体
6) receptor gene
受体基因
1.
Cloning and expression of the receptor gene (Bt-r_3) of the Bt toxic protein Cry1Ab in E. coli.;
Bt毒蛋白Cry1Ab受体基因Bt-r_3在大肠杆菌中的克隆和表达及特性分析
2.
Bt-R3, a gene of 5551, is a newly cloned cadherin-like receptor gene and its ORF (open reading frame) encodes 1715 amino acids.
Bt-R3受体基因是吴志平博士在其博士论文研究中新克隆到的钙粘蛋白类受体基因，它的cDNA序列全长5551bp，编码1715个氨基酸残基组成的Bt-R3前体蛋白。
补充资料：法尼醇
分子式：
CAS号：
性质：又称法尼醇，无环倍半萜醇。油状，沸点111℃(46.6Pa)，137℃(399.9Pa)。折射率1.4872。溶于大多数有机溶剂。广泛存在于多种植物挥发油中，如香茅油、橙花油、柠檬草油、玫瑰油、仙客来油、晚香玉油等。具盛甜鲜淡的花香，有蜜甜的玫瑰、铃兰气息，香气持久。由橙花椒酮经烯丙基重排而得。用于花香型、素心兰型日化香精，亦可用于食用香精起增浓、协调和稳定香气的作用。具有保幼激素功能。
CAS号：
性质：又称法尼醇，无环倍半萜醇。油状，沸点111℃(46.6Pa)，137℃(399.9Pa)。折射率1.4872。溶于大多数有机溶剂。广泛存在于多种植物挥发油中，如香茅油、橙花油、柠檬草油、玫瑰油、仙客来油、晚香玉油等。具盛甜鲜淡的花香，有蜜甜的玫瑰、铃兰气息，香气持久。由橙花椒酮经烯丙基重排而得。用于花香型、素心兰型日化香精，亦可用于食用香精起增浓、协调和稳定香气的作用。具有保幼激素功能。
说明：补充资料仅用于学习参考，请勿用于其它任何用途。
参考词条