Methods: Simvastatin orally disintegrating tablets were prepared by solid-states-dissolution technology,and three disintegrating equipments were used to detect the disintegration of orally disintegrating tablets in vitro,and also the relationship between disintegrating results:in vivo and in vitro was studied.

Determination of Related Substances in Simvastatin Tablets by HPLC;

Pharmacokinetics and bioequivalence of Simvastatin Tablets in healthy volunteers

Determination of simvastatin and its related substances in simvastatin dispersible tablets by HPLC;

Improved synthesis of simvastatin;

Preparation of sustained-release dropping pills of simvastatin and its dissolution rate;

Influence of Simvastain on insulin sensitivity of patients with acute coronary syndrome;

Remodeling of Transient Outward Potassium Channel in Left Ventricle of Rabbits with Heart Failure and Intervention with Losartan and Simvastain;

Affection of TNF-a、IL-1 and BNP level and heart function on chronic congestive heart failure combination treated with Simvastain and Valsartan

Effects of simavastatin on the endothelial function in patients with coronary heart disease;

Simavastatin with Zhimaishu for Treatment of Hyperlipidemia;

Experimental study of combining simavastatin with Zhimaishu(脂脉舒) in hyperlipidemia treatment;