1) P38 mitogen-activated protein kinase
丝裂酶原活化蛋白激酶
1.
Effect of acupuncture on modulation of extracellular signal regulated kinase 1/2 and P38 mitogen-activated protein kinase signal transduction pathways in subcutaneous fascia and spinal medulla of rats
针刺对大鼠局部筋膜和脊髓细胞外信号调节激酶1/2和P38丝裂酶原活化蛋白激酶信号通路的影响
2) MAPK-activated protein kinase
丝裂原活化蛋白激酶激活蛋白激酶
3) Mitogen activated protein kinase
丝裂原活化蛋白激酶
1.
Influence of leech extract on signal transduction of human retinal pigment epithelial cell mediated by p38 mitogen activated protein kinase
水蛭提取液对p38丝裂原活化蛋白激酶介导的人视网膜色素上皮细胞信号转导途径的影响
2.
Mitogen activated protein kinase(MAPK)is wide spread in all of eucells and responsible for transfering some ecto-signs into cellular nucleus.
丝裂原活化蛋白激酶(MAPK)信号通路,广泛存在各种真核细胞中,可将胞外刺激信号传递给胞核,是细胞应激和损伤反应的主要信号通路。
3.
Mitogen activated protein kinase(MAPK)signal pathw ay generally resides in mammal cells,which has close relationship with many pathological courses in the body such as diabetes,cardiovascular diseases,brain development and s o on and has become the hot spot in life science since 1990s.
丝裂原活化蛋白激酶(MAPK)信号通路广泛存在于哺乳动物细胞中,与机体多种生理病理过程(如糖尿病,心血管疾病,脑发育等)密切相关,是20世纪90年代以来生命科学研究的热点。
4) P38MAPK
P38丝裂原活化蛋白激酶
1.
Expression of activated P38MAPK in retina of rat after crushing injury;
大鼠视神经损伤视网膜内P38丝裂原活化蛋白激酶活性的表达
2.
Changes of phosphorylated p38MAPK in the murine model of traumatic hemorrhagic shock with endotoxin;
大鼠创伤失血性休克复合内毒素打击模型中p38丝裂原活化蛋白激酶磷酸化水平的改变
3.
Objective:To explore the dynamic expression of P-selectin,MCP-1,NF-κB and p38MAPK in the renal tubules of diabetic rats and to investigate their mutual relationship and roles in the pathogenesis of diabetic nephropathy.
目的:观察糖尿病大鼠肾小管p38丝裂原活化蛋白激酶(p38MAPK)、NF-κB、I-κB、P选择素和MCP-1表达的动态变化,探讨相互间关系及在糖尿病性肾病(DN)发生发展中的作用。
5) mitogen-activated protein kinase
丝裂原活化蛋白激酶
1.
c-erbB_2 and c-myb induce oocyte maturation via activation of mitogen-activated protein kinase and maturation promoting factor;
原癌基因c-erbB_2和c-myb经丝裂原活化蛋白激酶和成熟促进因子途径调节卵母细胞的成熟
2.
Celecoxib inhibits proliferation of polycystic kidney cyst lining epithelial cells through blocking mitogen-activated protein kinase signal transduction pathways;
塞来昔布通过阻断丝裂原活化蛋白激酶信号途径抑制多囊肾囊肿衬里上皮细胞增殖
3.
Mitogen-activated protein kinase regulated hypoxia-inducible factor 1α in hypoxia-induced pulmonary hypertension in rats;
丝裂原活化蛋白激酶调节缺氧诱导因子1α对大鼠缺氧性肺动脉高压的作用
6) MAPK
丝裂原活化蛋白激酶
1.
The Role of MAPKs and MKP-1 in Cardiomyopathy and Apoptosis of Cardiac Myocyte;
丝裂原活化蛋白激酶和磷酸酯酶-1在心肌病和细胞凋亡中的作用
2.
Objective: To investigate the activity and possible role of MAPK in mesangial cells in response to high glucose and to research the mechanism of diabetes nephopathy.
目的:探讨高糖对人肾小球系膜细胞丝裂原活化蛋白激酶(MAPK)活性的影响及MAPK在人肾小球系膜细胞的纤维结合蛋白(FN)分泌和c鄄fos表达中的作用。
3.
Aim This study is designed to analyze the influence of L-arginine (L-Arg) on expression level of angiotensin Ⅱ receptors (ATR) and the mitogen-activated protein kinase (MAPK) in cultured cardiomyocytes, with the intention to clarify the mechanisms relative to L-Arg s inhibitory effects on formation of cardiac hypertrophy.
目的探讨L-精氨酸(L-arginine,L-Arg)对心肌细胞血管紧张素Ⅱ受体(angiotensin Ⅱ receptor,ATR)及丝裂原活化蛋白激酶(mitogen-activated protein kinase,MAPK)表达的影响,进而阐述L-Arg对病理性心肌肥大的影响作用及相关机制。
补充资料：蛋白激酶A
分子式：
CAS号：
性质：一种依赖cAMP的蛋白激酶。它由4个亚基组成，2个相同的调节亚基(R)和2个相同的催化亚基(C)。有两种同酶形式，I型和Ⅱ型，它们之间的催化亚基相同而调节亚基不同。四聚体全酶(R2C2)处于无活性状态，当4分子cAMP结合到两个调节亚基的结合部位时，无活性的四聚体介离，产生具有酶活性的游离催化亚基以及调节亚基与cAMP的复合物(R-cAMP)。PKA的作用底物包括膜蛋白、胞浆蛋白和核内蛋白，使多种蛋白质的丝氨酸或苏氨酸羟基的磷酸化，并由此引起一系列生化反应。
CAS号：
性质：一种依赖cAMP的蛋白激酶。它由4个亚基组成，2个相同的调节亚基(R)和2个相同的催化亚基(C)。有两种同酶形式，I型和Ⅱ型，它们之间的催化亚基相同而调节亚基不同。四聚体全酶(R2C2)处于无活性状态，当4分子cAMP结合到两个调节亚基的结合部位时，无活性的四聚体介离，产生具有酶活性的游离催化亚基以及调节亚基与cAMP的复合物(R-cAMP)。PKA的作用底物包括膜蛋白、胞浆蛋白和核内蛋白，使多种蛋白质的丝氨酸或苏氨酸羟基的磷酸化，并由此引起一系列生化反应。
说明：补充资料仅用于学习参考，请勿用于其它任何用途。
参考词条