AIM: To study the concentration of morroniside in rat serum after oral administration of Liu-wei Di-huang pills(LDP), to investigate the effect of morroniside on proliferation and differentiation of rat preadipocytes.

Methods Rat preadipocytes were cultured.

Study on the expression levels of estrogen receptor of fat cell in different parts of body;

Method: To apply the technique of low-energy laser dissolving fat-layer to measure SD aged rats fat-layer liquefacient degree;with measure take stock of the effect on dissolved fat-layer;pathology slices observe the change of fat cell membrane s structure;project-elect.

To study the effect of tumor necrosis factor alpha (TNF α) on glucose uptake and insulin receptor substrate I (IRS-1) tyrosine phosphorylation in cultured fat cells in order to provide new experimental data for probing into the pathogenesis of IR in polycystic ovary syndrome (PCOS).

IL-6 on expression of leptin mRNA in orbital differentiated adipocytes of thyroid associated ophthalmopathy;

Pioglitazone attenuate oxidative stress induced insulin resistance in adipocytes;

Effect of different parts of Portulace oleracea on the levels of TNF-α and IL-6 in the supernatant of cultured adipose cell;

The expression of estrogen receptor in adipose cell and the relation between ertrogen receptor and the adipose distribution in human body;

The ectogenetic bovin recombination leptin as 5 mg/L was added to the culture media of the grater omentum anterior adipose cell sampled from new-born calf to determine the effect of leptin on the form of adipose cell and the content of triglyceride in the cell.