1) Smad anchor for receptor activation
Smad锚着蛋白
1.
Smad anchor for receptor activation(SARA) is known as Smad cofactor that interacts directly with Smad2/3 and functions to recruit Smad2/3 to the TGF-β receptor.
SARA是Smad锚着蛋白,可与Smad2/3直接结合,募集Smad2/3至TGF-β受体,是TGF-β信号通路中重要的衔接蛋白。
2) Smad protein
Smad蛋白
1.
Objective To investigate the effect of ligustrazine on the intracellular translocation of Smad protein in HSC-T6 cell line.
目的探讨川芎嗪对HSC-T6细胞Smad蛋白细胞内转位的影响。
2.
Objective To investigate the localization of Smad protein 2, 3, 6, 7 and their changes of expression in experimental interstitial fibrosis model in rats.
抗Smad蛋白表达下降可能是该模型TGF-β1致肾纤维化作用的主要原因。
3.
Smad protein is the important substrate of TGFβ1.
TGFβ1(transforming growth factor beta 1,TGFβ1)是目前公认最强的致肝纤维化的细胞因子,Smad蛋白是目前发现的TGFβ家族受体激酶的关键作用底物,TGFβ1激活肝星状细胞(hepatic stellate cell,HSC)的信息转导须经过Smad蛋白家族,才能将信息传入细胞核内,启动胶原基因表达而引起肝纤维化。
3) Smad
Smad蛋白
1.
TGF β plays a crucial role in the renal fibrosis and Smads mediate the intracellular signal transduction of TGF β.
TGF- β是肾纤维化发生、发展中的必需因子 ,Smad蛋白是 TGF- β受体的胞内激酶底物 ,介导了 TGF- β的胞内信号转导。
2.
Method:Detection the expression of Smad protein in fibroblasts before the expression of αsmooth muscle actin.
方法:利用免疫组织化学方法检测成纤维细胞表达α平滑肌肌动蛋白之前表达Smad蛋白的改变。
3.
The Smad family of proteins has recently been identified as a predominant signaling pathway by which TGF-B activates the transcription of several well-known TGF-B-inducible genes.
近年来,Smad蛋白家族被认为是一些TGF-β诱导基因的主要信号通路,其中TGF-β起转导作用。
4) Smad proteins
Smad蛋白
1.
Effect of carvedilol on expression of Smad proteins mediated by AngⅡ in cardiac fibroblasts;
卡维地洛对血管紧张素Ⅱ介导的心脏成纤维细胞Smad蛋白表达的影响
2.
Smad proteins possess special structure and property and play significant roles in TGF-β signal transduction pathway.
Smad蛋白是转化生长因子-β(transforming growth factor-β,TGF-β)信号转导通路中关键的介质,TGF-β通过结合细胞表面特异性受体而启动下游的Smad蛋白传导通路。
3.
Objective To explore the molecular mechanisms of the Smad proteins in lung cancer development, we constructed the Smad proteins eukaryotic expression vectors and detected their expressions in the SV40-transformed embryonic kidney 293T cell line.
目的:探索Smad蛋白在肺部肿瘤形成过程中的分子机制,构建带FLAG标签的smad1、2、3、4的真核表达载体,并检测其在293T细胞中的表达。
5) protein Smads
蛋白质Smad
6) Smad proteins
Smad蛋白质类
补充资料：[3-(aminosulfonyl)-4-chloro-N-(2.3-dihydro-2-methyl-1H-indol-1-yl)benzamide]
分子式：C16H16ClN3O3S
分子量：365.5
CAS号：26807-65-8
性质：暂无
制备方法：暂无
用途：用于轻、中度原发性高血压。
分子量：365.5
CAS号：26807-65-8
性质：暂无
制备方法：暂无
用途：用于轻、中度原发性高血压。
说明：补充资料仅用于学习参考，请勿用于其它任何用途。
参考词条