A new type of silicone oil modified with amino was synthesized with octamethylcyclo tetrasiloxane and the hydrolysis product ofγ-piperazinepropylmethyldimethoxysilane(HD-110 )in the catalyst of potassium hydrate.

A novel hydroxyl terminated aminosilicone oil was synthesized using octamethylcyclo tetrasilox-ane(D4) and the hydrolysis product of γ-piperazinepropylmethyldimethoxysilane(HD-110) as raw material and potassium hydrate as catalyst.

Taking advantage of the steric effect of nitrogen atoms in 2-methylpiperazine, selective monobenzoylate on the nitrogen atoms were investigated by five synthetic routes.

Synthesis and Biological Activity Study on N-(3,4-Dimethox yphenylethyl)-4-Subtituted Phenylpiperazine-1-Acetamide Series as α_1-Adrenoceptor Antagonists;

Synthesis and Biological Activities of N-(5-Methoxy-1H-indole-3-ethyl)-4-Subtituted Phenylpiperazine-1-acetic Amide Derivatives as α_1-Adrenoceptor Antagonists;

Alkyl substituted phenylpiperazine derivatives are important intermediates of phenylpiperazine compounds.

~(13)C NMR chemical shifts of nine new synthesized 1-benzyl-piperazine was reported.

Preparation of Chiral 2-Methylpiperazine;

The continuous synthesis of 2-methylpiperazine was studied,using the self-prepared N-(β-hydroxy -propyl)-ethylenediamine as the starting material.