Endogenous EETs are degraded by soluble epoxide hydrolase(sEH) and pharmacological inhibition of sEH is a potential approach to enhance EET-mediated vascular protection.

Effects of Soluble Epoxide Hydrolase Inhibitor on Pressure Overload Induced Cardiac Hypertrophy in Mice;

Isolation of a bacterium producing epoxide hydrolase and optimization of fermentation conditions;

Progresses in research work of epoxide hydrolase were briefly introduced.

Important biocatalytic reactions involving epoxides included epoxide hydrolase mediated kinetic resolution,leading to the formation of diols and enantiopure remaining substrates,and enantioconvergent enzymatic hydrolysis,which given high yields of a single enantiomer from racemic mixtures.