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1)  SHP2/CyclinD1/CDK4 pathway
SHP2/CyclinD1/CDK4通路
1.
The mRNA and protein levels of SHP2/CyclinD1/CDK4 pathway in A549 cell line and the sublines were determined by RT-PCR and Western-blot.
照射完成后对存活细胞单克隆化分别命名为AS49-S1和AS49-S2,采用克隆形成实验测定两种细胞亚系及亲本A549细胞的放射敏感性,流式细胞术检测细胞周期特征,RT-PCR和Western blot分别测定3种细胞SHP2/CyclinD1/CDK4通路的表达。
2)  CDK4-pRB-E2F1 pathway
CDK4-pRB-E2F1通路
1.
CDK4-pRB-E2F1 pathway may mediate Aβ_(1-40)-induced apoptosis in rat cortical neurons;
CDK4-pRB-E2F1通路是Aβ_(1-40)诱导皮层神经元凋亡的可能途径
3)  Cyclin D1
cyclinD1
1.
Expression of survivin,cyclin D1 and PTEN protein in gastrointestinal stromal tumors and their significance;
胃肠间质瘤中survivin、cyclinD1和PTEN蛋白的表达及病理意义
2.
Expression of AKT2, Cyclin D1, and MMP-9 and Their Correlations to Clinicopathologic Features of Non-small Cell Lung Cancer;
非小细胞肺癌组织中AKT2、CyclinD1、MMP-9表达及其与临床病理因素的关系
3.
Expressions of FHIT and cyclin D1/CDK4 in oral cancer and oral precancerous lesions;
口腔癌及癌前病变中FHIT与cyclinD1/CDK4表达的相关性研究
4)  CyclinD 1
CyclinD1
1.
Objective: To investigate the expression of Bax and CyclinD 1 in Non-small cell lung cancer(NSCLC) and their clinical significance.
目的 :探讨促凋亡基因Bax和促增殖基因CyclinD1在非小细胞肺癌中的表达及意义。
2.
Objective:To investigate the clinical pathological features of histological typing and grading and the correlationship between ER,PR and the expression of p16,CyclinD 1, and C-erbB 2 proteins.
目的 :探讨乳腺癌组织分型、分级等临床病理特征和ER、PR与 p16、CyclinD1、C -erbB2 蛋白表达的关系。
3.
Objective:To investigate the expression and significance of Ki-67 and cyclinD 1 in transitional cell carcinoma of bladder(TCC).
目的 :探讨膀胱移行细胞癌组织中Ki 6 7抗原和cyclinD1的表达及其临床意义。
5)  Cyclin D 1
CyclinD1
1.
AIM: To investigate the expression of Cyclin D 1 in proliferative endometrium and endometrial carcinoma and its significance.
目的 :探讨细胞周期素D1(CyclinD1)蛋白在增生性子宫内膜及子宫内膜癌中的表达及意义 。
2.
The expressions of PCNA and cyclin D 1 in the HepA liver carcinoma cells were detected by immunohistochemistry.
方法 :建立小鼠HepA肝癌模型 ,进行莪术油抑癌试验 ,并用免疫组化法检测细胞增殖核抗原 (PCNA)、细胞周期素D1(cyclinD1)的表达 ,探讨莪术油抑制小鼠肝癌的分子机理。
3.
Objective To study the expression and clinicopathologic relation of Cyclin D 1 in breast cancer.
目的 探讨细胞周期素D1 (CyclinD1 )在乳腺肿瘤组织中的表达及临床病理相关性。
6)  cyclinDl
cyclinD1
1.
Significance of P16,cyclinDl protein expression in gastric carcinoma and precancerous lesion;
胃癌及癌前病变中P16、cyclinD1蛋白的表达及其意义
2.
Objective: To study the differences in aberration of pl6 and cyclinDl gene in patients with non-small cell lung cancer (NSCLC) between Xuanwei county and Kunming city.
目的:研究p16、cyclinD1基因在宣威、昆明两地肺癌患者中遗传变异的差异性,探讨p16、cyclinD1基因在肺癌发生发展中的作用。
3.
Methods: cyclinDl, CDK4, PCNA, p16 andp27 proteins were detected by immunohistochemical staining in total 107 samples of chronic hepatitis, liver cirrhosis, paratumor cirrhosis, hepatocellular carcinoma (HCC), and normal liver tissues.
方法:应用免疫组织化学检测正常肝组织、慢性肝炎、肝硬化、癌周肝硬化和肝癌共107例标本中cyclinD1、CDK4、PCNA、p16、p27蛋白的表达情况。
补充资料:[3-(aminosulfonyl)-4-chloro-N-(2.3-dihydro-2-methyl-1H-indol-1-yl)benzamide]
分子式:C16H16ClN3O3S
分子量:365.5
CAS号:26807-65-8

性质:暂无

制备方法:暂无

用途:用于轻、中度原发性高血压。

说明:补充资料仅用于学习参考,请勿用于其它任何用途。
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