1) recombinant human platelet derived growth factor-BB
重组人血小板衍生生长因子-BB
1.
Our former studies have showed that the number of osteoclasts and the expression of integrin alphavbeta3 were obviously increased in the compression sides of the orthodontic tooth movement model rats after local injection the low does of recombinant human platelet derived growth factor-BB (rhPDGF-BB), meanwhile, it accelerated the rate of orthodontic tooth movement.
前期系列实验表明:在大鼠正畸牙牙周局部注射低剂量重组人血小板衍生生长因子-BB(recombinant human platelet derived growthfactor-BB,rhPDGF-BB)后,压力侧破骨细胞计数增加,整合素α_vβ_3表达增强,从而加速了正畸牙的移动。
2) platelet-derived growth factor BB
血小板衍生生长因子BB
1.
Objective:To explore the relationship among vascular endothelial growth factor C(VEGF-C),platelet-derived growth factor BB(PDGF-BB),lymphangiogenesis and lymph node metastasis in human non-small cell lung cancer(NSCLC).
目的:探讨血管内皮生长因子C(VEGF-C)和血小板衍生生长因子BB(PDGF-BB)在非小细胞肺癌(NSCLC)中的表达与淋巴管生成和淋巴结转移的关系。
2.
Objective To investigate the intracellular calcium concentration alteration induced by platelet-derived growth factor BB(PDGF-BB) and the mechanism of ion flux in cultured glomerular mesangial cells.
目的 研究血小板衍生生长因子BB(PDGF-BB)引起的肾小球系膜细胞内游离钙浓度变化及其离子流动机制。
3) platelet derived growth factor-BB
血小板衍生生长因子-BB
1.
Objective To explore the effects of platelet derived growth factor-BB(PDGF-BB)and basic fibroblast growth factor(bFGF)on alkaline phosphatase(ALP)activity in human periodontal ligament cells(hPDLCs)in vitro.
目的探讨血小板衍生生长因子-BB(PDGF-BB)和碱性成纤维细胞生长因子(bFGF)对人牙周膜(PDL)细胞碱性磷酸酶(ALPase)活性的影响。
4) Platelet-derived growth factor-BB
血小板衍生生长因子-BB
1.
MethodsHepatic stellate cells (HSCs) isolated from rats were primarily cultured in uncoated plastic culture dish for 7 days, then were incubated with 10~ -6 mmol/L SA-B and stimulated with 10 ng/ml transforming growth factor-β_1 (TGF-β_1) or platelet-derived growth factor-BB (PDGF-BB).
方法分离大鼠肝星状细胞(HSC),于无包被塑料培养皿中原代培养7天,继以10-6mmol/L SA-B孵育,再加10ng/ml的转化生长因子β1(TGF-β1)或血小板衍生生长因子-BB(PDGF-BB)刺激。
5) PDGF-BB
血小板衍生生长因子-BB
1.
Objectives:To investigate the inhibitory effect of Danshengsu on proliferation、collagen typeⅠsynthesis and Phosphorylated extracellular signal- regulated kinase 1/2 (P-ERK1/2)expression of rat hepatic stellate cell ( HSC ) stimulated by platelet derived growth factor-BB (PDGF-BB),and to elucidate the molecular mechanism of Danshensu against hepatic fibrosis.
目的观察丹参素对血小板衍生生长因子-BB (platelet derived growth factor-BB PDGF-BB)刺激大鼠肝星状细胞(hepatic stellate cell HSC )增殖、Ⅰ型胶原合成、磷酸化细胞外信号调节激酶1/2(Phosphorylated extracellular signal- regulated kinase 1/2 ,P-ERK1/2)表达的影响,探讨丹参素抗肝纤维化的分子机制。
2.
Real-time fluorescence quantitative PCR method was used to determine the effects of Qingfei oral liquid medicated serumon on the expression of TGF-β_1 and PDGF-BB mRNA genes.
观察清肺口服液含药血清对RSV感染后人胚肺成纤维细胞转化生长因子-β_1和血小板衍生生长因子-BB mRNA基因表达的影响。
6) platelet derived growth factor BB
血小板衍生生长因子BB
1.
Objective To investigate the relationship between the expression of platelet derived growth factor BB(PDGF-BB)、vascular endothelial growth factor C(VEGF-C)and the clinicopathologic parameters in colonic carcinoma,and to explore the difference of VEGF-C and PDGF-BB expression in primary tumor and metastatic lymph node.
目的探讨结肠癌组织中血小板衍生生长因子BB(PDGF-BB)、血管内皮生长因子C(VEGF-C)的表达,及其与肿瘤临床病理参数之间的关系;分析在结肠原发癌与相应淋巴结转移癌中VEGF-C、PDGF-BB表达是否存在差异。
2.
Significance of platelet derived growth factor BB on the development of cerebral vasospasm;
目的 探讨血小板衍生生长因子BB(PDGF BB)在蛛网膜下腔出血 (SAH)后的表达及其对正常脑血管的影响 。
补充资料：血小板衍生生长因子
分子式：
CAS号：
性质：platelet derired growth factor；PDGF 贮存于血小板α颗粒中的一种碱性蛋白质，是一些细胞，如纤维母细胞、平滑肌细胞、神经胶质细胞的促细胞分裂剂。包括PDGF-I和PDGF-II，二者所含蛋白质相同，仅糖苷含量各异，它们是由两个不同的多肽链由二硫键结合而成的二聚体，其中A链较大(PDGF-I中的A链为17 000，PDGF-II中的A链为15 000)，B链较小(14 000)。由血小板纯化得到的PDGF为AB、BB双聚体，许多肿瘤细胞中的PDGF为AA双聚体。目前认为PDGF在伤口愈合、胆固醇与磷酯合成的调节、动脉粥样硬化等多种生理及病理过程中起重要作用。
CAS号：
性质：platelet derired growth factor；PDGF 贮存于血小板α颗粒中的一种碱性蛋白质，是一些细胞，如纤维母细胞、平滑肌细胞、神经胶质细胞的促细胞分裂剂。包括PDGF-I和PDGF-II，二者所含蛋白质相同，仅糖苷含量各异，它们是由两个不同的多肽链由二硫键结合而成的二聚体，其中A链较大(PDGF-I中的A链为17 000，PDGF-II中的A链为15 000)，B链较小(14 000)。由血小板纯化得到的PDGF为AB、BB双聚体，许多肿瘤细胞中的PDGF为AA双聚体。目前认为PDGF在伤口愈合、胆固醇与磷酯合成的调节、动脉粥样硬化等多种生理及病理过程中起重要作用。
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