Recent advance on the modification of MCM-41 mesoporous sieve by incorporation,function and support were reviewed,and its application in chemical engineering,environmental protection and biological medicine were summarized.

The silica MCM-41 mesoporous molecular sieve has some advantages,for instance,stable framework,ordered pore canal,narrow distrbution of pore diameter,but its hydrothemal stability is terrible,acidity is inferior,pore diameter is not big enough and it isn't suitable for large molecule reaction.

β-Tetra-(p-carboxyphenoxy)phthalocyanine cobalt((p-HOOCPhO)4PcCo)was loaded on MCM-41 mesoporous molecular sieves by impregnation to prepare(p-HOOCPhO)4PcCo/MCM-41 catalyst which was used in oxidation of ethanethiol.

Trypsin was immobilized on the Mesoporous Molecular Sieve MCM-41 with the aid of the coupling agent,glutaraldehyde.

Using sodium silicate as silicate and surfactant C16H33(CH3)3NBr as structural template,the preparation of mesoporous molecular sieve MCM-41 was accomplished successfully and with tetrabutyltitanate as precursor and aqueous vapour as activation medium,the inner surface of mesoporous sieve MCM-41 was modified by nano-titanate in an infrared image furnace.

Using industrial sodium silicate as silicate and surfactant C16H33(CH3)3NBr as structural template, the preparation of mesoporous molecular sieve MCM-41 was accomplished successfully by room temperature crystallization method, and and with tetrabutyltitanate as precursor, TiO2/MCM-41 loaded nanometer complex material was prepared by sol gel method and chemistry liquid deposit process.