Some compounds containing 1-benzothiepine skeleton are reported to exhibit good biological activities,but their occurrence in nature is even more deficient,and are obtained mainly by organic synthesis.

Synthesis, Crystal Structure, Antimicrobial Activity and Structure Activity Relationship of 3-Ethoxycarbonyl-1,5-benzothiazepines

1,5-benzothiazepine is a kind of compound which has important physiological activities.

1,5-benzothiazepines are a kind of compounds with important biological activities, such as treating for neural and heart diseases.

Synthesis of 2-Phenyl-1,2,3-triazol-4-yl[1,2,4] Oxadiazolo[4,5-a][1,5] benzothiazepine Derivatives;

However, the addition of co-catalysts such as benzothiazepines derivatives can increase the ratio of p-/o- isomers.

The reaction of 2 - phenyl - 4 - aryl -2,3- dihydro -1,5- benzodiazepine with ethyl diazoacetate using power Cu as a catalyst gives a normal cycloaddition product , azirino - benzodiazepine (I) , and an unprecedent product pyrro - benzodiazepine (II) .