1) PI3K signal pathway
PI3K信号通路
1.
Cell immunofluorescence, western blot, real-time PCR and real-time PCR array were used to determine the regulation of PI3K signal pathway by As2S2 at the levels of transcription and protein.
方法以不同浓度的As2S2作用白血病细胞不同时间后，应用MTT试验检测As2S2对白血病细胞的增殖抑制；流式细胞术及MGG染色检测As2S2及PI-103单用或联用时对白血病细胞、脐血单个核细胞及白血病患者骨髓单个核细胞的分化及凋亡诱导作用；克隆形成实验检测As2S2对白血病细胞克隆的清除能力；细胞免疫荧光、Western blot、Real-time PCR及Real-timePCR array检测As2S2对PML和PI3K信号通路中多个信号分子的蛋白及转录水平的调控。
2) IGF-PI3K-Akt signaling pathway
IGF-PI3K-Akt信号通路
1.
Recent evidence suggests that normal and exercise-induced cardiac growth are regulated in large part by IGF-PI3K-Akt signaling pathway.
近年来,研究表明心肌的正常生长以及运动诱导的心肌生理性肥大,主要是通过IGF-PI3K-Akt信号通路进行信号转导。
3) PI3K/Akt signal pathway
PI3K/Akt信号通路
1.
Prosaposin pro-tein was proved to activate the PI3K/Akt signal pathway,upregulate the phosphorylative activity of Akt at Serine 473,downregulate the expression of P27Kip1 gene,upregulate the expression of Cyclin D1 gene and then promote the G1/S tran-sition,and upregulate the expression of survival genes cIAP1 and cIAP2 and then prevent cell apoptosis.
1 in NIH3T3阴性对照细胞株和过表达prosaposin的Psap-Myc in NIH3T3细胞株为模型,噻唑蓝(MTT)比色法检测prosaposin对细胞增殖的影响;Annexin V联合碘化丙啶(Propidium iodide,PI)法检测血清饥饿状态下prosaposin对细胞凋亡的影响;Western blotting检测PI3K/Akt信号通路中蛋白磷酸化水平的变化;Real-time PCR检测PI3K/Akt信号通路下游靶分子表达水平的改变。
4) FAK/PI3K/Akt pathway
FAK/PI3K/Akt信号通路
5) PI3K/Akt signaling pathway
PI3K/Akt信号通路
1.
Effects of PI3K/Akt signaling pathway on vascular endothelial function and interventional effects of erythropoietin
PI3K/Akt信号通路对血管内皮功能的影响及促红素干预
2.
Role of PI3K/AKT signaling pathway in hepatic ischemia-reperfusion-induced lung injury in rats
PI3K/AKT信号通路在全肝缺血再灌注大鼠肺损伤中的作用
补充资料：PI
聚酰亚胺是由4，4’-二氨基二苯醚与均苯四甲酸酐反应先得到高分子量且能溶于极性溶剂的预聚体——聚酰胺酸，然后在高温下脱水环化制得。不溶性聚合物．淡黄色粉末，细度＜250um，表观密度0．35。耐高低温，性能优异．在－269～400 ℃范围内保持较高的机械性能，热变形温度360℃(1.82MPa)。使用温度-240～260℃。耐辐射性极好。耐磨性良好，能耐大多数溶剂，但易被浓酸、浓碱水解。在沸水和蒸汽的长时间作用下能被破坏。
说明：补充资料仅用于学习参考，请勿用于其它任何用途。
参考词条