Aim To use the epiderm as the seeding cell in the skin tissue engineering, and choose the optimized conditions for the isolation and growth of human epidermal cells in culture.

Many researches show that MSCs acts very well as seeding cells in skin tissue engineering to repair skin defect in animal models by autotransplantation or allotransplantation into immunodeficiency animals.

However, the tissue engineered skin have not the physiological function of normal skin because they are absent of skin appendiges, such as hair follicle, sweat gland and sebaceous gland.

Seeding cells isolated from skin biopsy and natural or synthetic materials are used to construct tissue engineered skin.

Construction of tissue-engineered skin with BMSCs and tissue-engineered acellular dermal matrix;

Experimental research of histological difference between tissue-engineered skin and normal human skin

Effect of Rumo Shengji San on Skin Defect After Repair with Tissue-engineered Skin

Percutaneous penetration of ketoprofen and ketoprofen isopropyl ester through a tissue engineering skin reconstructed with HaCaT cells;

The progress of study on the biology behavior of epidermal stem cell as the seed cell of tissue engineering skin;

Method of detecting tissue engineering skin viability;

The use of tissue engineering skin in study of percutaneous drug absorption;