Co-injection with XCL1 plasmid enhanced the protective immune response against CVB3 conferred by DNA vaccines;

A study of co-injection of HPV DNA vaccine with IL-15 expression plasmid inducing specific lymphoproliferation;

Study of cell-mediated immune response induced by HPV DNA vaccine in combination with IL-15 expression plasmid;

Immunity of genetic vaccine based on alpha virus replicase to human melanoma;

Immunological role of genetic vaccine of mouse mastocytoma;

Objective To explore the enhancing effect of RNA replicase of alpha virus on the immune effect of genetic vaccine in order to obtain its optimal form.

Expression of human PH-20 gene vaccine in NIH3T3 cells and the mouse skeletal muscle;

Expression of gene vaccine of hSAMP32 in the mouse skeletal muscle medicated by gene gun;

Immuno-protection efficacy of Mtb8.4 gene vaccine with signal peptide against TB in mice;

This review discussed the birth of genetic vaccines,their advantages and approaches designed to enhance their efficacy including reasonable vector s design, coexpression with cytokines and costimulatory factors,reasonable routes of vaccination etc.

The genetic vaccines have became a hotspot in field of vaccine development since the first report of genetic vaccines was published in early 1990s .

In order to detect the integrity of migrating instance in migrating workflows system,an immune entity composed of self-set,detector-set,r-continuous bits match detection function and vaccine gene-set is defined based on artificial immunology principle.