Multiple signal transduction pathways converge on CREB,which plays an essential role in the formation of long-term memory and synaptic plasticity.

There are a lot of researches about the structure of long-term memory,which have been brought forward many models of long-term memory.

The psychological study on memory reveals that memory is a complicated cerebral phenomenon of processing information,which can be generally divided into three stages: sensory storage,short-term memory and long-term memory.