1) TD50 median toxic dose
半数中毒剂量
2) TD50
半数中毒量
3) toxic dosage
中毒剂量
1.
Methods A series of tests of pharmacodynamics, toxic dosage and lethal dosage was made with oral aqueous solution administration in mice, the reactions of mice with different doses at different times were observed.
结果测得小鼠的中毒剂量为585mg/kg,安全剂量为313mg/kg。
2.
OBJECTIVE To investigate the tissue distribution of clenbuterol at toxic dosage in rabbits,to assess its difference between toxic and therapeutic dosages.
目的:研究中毒剂量与治疗剂量克仑特罗在兔体内的组织分布,分析比较两者差异。
3.
OBJECTIVE To investigate the pharmacokinetic parameters of clenbuterol at toxic dosage, to assess its difference of pharmacokinetic parameters between toxic and therapeutic dosages.
目的研究克仑特罗在引起不良反应的大剂量下兔体内的药动学,探讨中毒剂量与治疗剂量的药动学参数存在的差异。
5) subthreshold doses
亚中毒阈剂量
1.
Objective: To explore the oxidative damage effects on postnatal rats exposed to subthreshold doses of chlorpyrifos and the mechanisms of CPF caused development neurotoxicity.
目的:研究新生鼠暴露亚中毒阈剂量毒死蜱(chlorpyrifos,CPF)诱导脑组织氧化损伤情况,探讨CPF导致神经发育毒性的作用机制。
6) LD50
半数致死剂量
1.
[Result] Ionic liquid Br caused the death of some mice,with the median lethal dose(LD50) after 24 h to female and male mice being 52.
[结果]离子液体[C8mim]Br引起了部分小鼠死亡,其对雌鼠的24 h半数致死剂量(LD50)为52。
2.
We established intra-peritoneal injection models of toluene and observed ethology,nervous excitation and LD50.
方法昆明鼠随机分成6组,8 000mg/kg,4 000mg/kg,2 000mg/kg,1 000mg/kg,500 mg/kg等不同剂量甲苯小鼠腹腔注射制作急性中毒模型,生理盐水对照组,染毒后观察24h一般行为学改变和4d、6d、8d、10d、12d、14d运用程控自主活动箱检测神经兴奋性变化,运用寇氏法公式计算药物半数致死剂量LD50。
3.
Methods:Acute toxicity was carried out in mice by oral and intravenous administration of sodium rosiglitazone and LD50 was calculated by Bliss method.
结果:小鼠尾静脉注射罗格列酮钠的半数致死剂量(LD50)值为619。
补充资料：半数中毒量
分子式：
CAS号：
性质：药物引起半数实验动物中毒的剂量。
CAS号：
性质：药物引起半数实验动物中毒的剂量。
说明：补充资料仅用于学习参考，请勿用于其它任何用途。
参考词条