1) parahemophilia
[,pærə,hi:mə'filiə]
副血友病
2) Hemophilia
[英][,hi:mə'filiə] [美][,himə'fɪlɪə]
血友病
1.
Diagnosis of Radiography Image of Arthropathies in Patients with Hemophilia;
血友病骨关节病变的X线诊断
2.
Testing study on Chinese version of "Canadian hemophilia outcomes-kids' life assessment tool";
“加拿大血友病儿童生活质量评估工具”中文版测试研究
3.
A review of holistic care model for patients with hemophilia in China and western countries;
我国及欧美血友病综合关怀模式的现状
3) hemophilia A
血友病A
1.
Prenatal diagnosis in eleven families with hemophilia A of inversion negative in intron 22 of factor Ⅷ gene;
非凝血因子Ⅷ基因内含子22倒位型血友病A家系11例产前诊断
2.
Recombinant Factor Ⅷ for Treatment of Patients with Hemophilia A in China;
基因重组人凝血因子Ⅷ在中国人血友病A患者中使用的研究
3.
Analysis and Detected the Intron Repeat Sequence of Facor Ⅷ Gene Polymorphism with Hemophilia A and Their Family Members;
血友病A家系因子Ⅷ基因内含子重复序列多态性的检测及分析
4) Hemophilia A and B
血友病A、B
5) Haemophilia
[英][,hi:mə'fɪliə] [美]['himə'fɪlɪə]
血友病
1.
Perioperative management of children suffering from haemophilia;
手术患儿合并血友病的围手术期处理
2.
Observations of Four Haemophilia Patients Infected with HIV;
4例血友病HIV感染者的追踪观察
3.
TSAH(Traumatic Subarachnoid Haemorrhage),is not seldom seen in forensic pathological practice and clinical medicolegal expertise however,relevant reports about the phenomena that haemophiliacs suffer from simple TSAH when their heads or faces are slightly hurt are relatively rare.
外伤性蛛网膜下腔出血(Traumatic Subarachnoid Haemorrhage,简称TSAH)在法医病理实践和临床法医鉴定中并不少见,但有关血友病人在头面部轻微外伤后出现单纯性TSAH的相关报道较少,在临床法医鉴定中有一起损伤和疾病同时存在的特殊案例,在该案例鉴定中有一些体会值得借鉴。
6) Haemophilia B
血友病B
1.
Haemophilia b is a kind of serious cruor-defective inhering diseaes.
血友病B是一种严重的凝血功能缺陷遗传病 ,由于现行的治疗方法对血友病B的治疗效果均不令人满意。
2.
In order to establish coagulation factor Ⅸ gene knockout mouse for human haemophilia B, 2×105 phage plaques of 129Sv mouse genomic library were screened with plaque in situ hybridization screening with 32P-labeled cDNA probe 5 positive clones were finally obtained.
为了利用ES细胞基因打靶技术建立人血友病B的转基因小鼠模型,用小鼠FIX基因cDNA为探针,筛选129Sv小鼠的基因组DNA噬菌体文库,从2×105个噬斑中得到5个独立的阳性噬菌体克隆。
补充资料:血友病
血友病 hemophilia 先天性凝血因子缺乏引起的出血性疾病。分甲、乙、丙3型,分别因缺乏凝血因子Ⅷ、Ⅸ和Ⅺ所致。血友病甲的发病率是乙的7倍,二者均通过性染色体隐性遗传使男性发病和女性传递,若男性病人与健康女性结婚,所生男孩均健康,而女孩均为传递者,若传递者女性与健康男性结婚,所生男孩一半为病人,一半为健康者,女孩一半为传递者,一半为健康者。血友病丙少见,是常染色体不全隐性遗传,男女均可发病,出血不重。部分病人无家族遗传史,可能是基因突变所致,发病原因未明。多数病人从小就有自发出血或轻伤后出血不止,主要为关节出血、肌肉血肿和深部血肿,也可有便血和尿血等。反复关节出血后可引起关节变形,最后丧失功能,造成残疾。病人凝血时间和激活的部分凝血活酶时间延长 ,而凝血酶原时间正常,通过纠正试验可区别3种血友病:硫酸钡吸附血浆能纠正而血清不能纠正者为血友病甲;血清能纠正而硫酸钡吸附血浆不能纠正者为血友病乙;均能纠正者为血友病丙。治疗主要是用新鲜全血、血浆或纯的凝血因子冷沉淀物替代治疗,甲氰咪胍和DDAVP对轻病人有效。今已对传递者在妊娠中期用胎血测凝血因子活性或用基因诊断方法以决定是否终止妊娠。 |
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