Studies on the Chiral Structure of Thiazolidine Ligands and Their Application to Asymmetric Hydrosilylation of Acetophenone;

Five N tetrahydrobenzothiazolyl imines have been synthesized by the condensation of 4,5,6,7 tetrahydro 2 benzothiazolamine with aromatic aldehydes and the reactions of imines respectively, with thioglycollic acid obtained five thiazolidones.

According to the principle of superposition activity, in this article, we have synthesized a series of thiazolidone and acylthiourea derivatives which are not reported in the literature by introducting 1,2,3-triazole-based, 1,3,4–thiadiazole and dibenzo into acetyl-hydroxy acyl thiazolidoneand thiourea derivatives through the promotion of ultrasonic radiation.

Sixty-six 1,3-thiazolidine derivatives, fifty-six of which are novel compounds, were prepared based on 1,3-thiazolidine as the lead compound and their structures were confirmed by IR, ~1H NMR, MS and elemental analysis.