2) antiepileptic
['ænti,epi'leptik]
抗癫痫药
1.
Synthesis of the antiepileptic tiagabine hydrochloride;
新型抗癫痫药盐酸噻加宾的合成
2.
Starting from tetrafuran, 2_(4_Aminosulfonylphenyl)_4H_1,2_thiazine_1_dioxide, an antiepileptic drug with special structure, was obtained via esterification, sulphonation, chloridization, condensation and cyclization.
以四氢呋喃为原料 ,经酯化、磺化、酰氯化、缩合、环化等步骤 ,合成了化学名为 4_(四氢_2H_1,2_噻嗪基_2 )苯磺酰胺_S_S_二氧化物的抗癫痫药舒噻嗪 (sulthiame) ,通过IR、1HNMR和元素分析对其结构进行了表
3.
Lamotigine is a new and specific antiepileptic.
拉莫三嗪是一种新型的特效抗癫痫药，我国对该药的应用完全依赖于从英国进口。
3) antiepileptic
['ænti,epi'leptik]
抗癫痫
1.
The relationship between serum carbamazepine concentration and its antiepileptic effect and adverse reactions;
卡马西平血药浓度与抗癫痫作用及不良反应的关系
2.
Research on anticonvulsive and antiepileptic effect of alpha-asarone and its mechanism
α-细辛脑的抗惊厥、抗癫痫作用及其机制研究
3.
The H-H correlated spectroscopy (H-H COSY), distortionless enhancement by polartization transfer spectrum (DEPT), heteronuclear multiple bond correlation (HMBC) and heteronuclear multiple quantum correlation (HMQC) spectra of 1-(2,6-diflurophenymethyl)-N-methyl-1H-1,2,3-triazole- 4-carboxamide which is a class of antiepileptic agent were reported and interpreted.
采用一维(1D)和二维(2D)核磁共振(NMR)技术对一种抗癫痫活性的化合物1-(2,6-二氟苯甲基)-N-甲基-1H-1,2,3-三唑-4甲酰胺的1H和13C NMR信号进行了归属。
4) anti-epilepsy
抗癫痫
1.
Felbamate is a new anti-epilepsy drug.
总结抗癫痫新药非氨酯及其重要中间体2-苯基-1,3-丙二醇的各种合成路线,并对各条路线作了评述,从而选出一条适合工业化的路线:以苯乙酸甲酯作原料,依次与甲酸甲酯、硼氢化钠反应生成2-苯基-1,3-丙二醇。
5) antiepileptic drug
抗癫痫药
1.
Gabapentin hydrochloride, an antiepileptic drug, was synthesized by Knoevenagel reaction from cyclohexanone and acetonitrile, Michael addition reaction, Pd-C catalytic hydrogenation and hydrolysis to give 2-hydroxy-2-azaspiro[4.
5]癸烷-3-酮,再经RaneyNi催化氢化还原和水解、成盐制得抗癫痫药盐酸加巴喷丁,总收率14%。
2.
Objective:The results of serum concentration monitoring of 4 antiepileptic drugs with 357 measurements in 164 epilepsy children were evaluated in order to guide clinical rational administration of these antiepileptic drugs.
目的:回顾性分析4种常用抗癫痫药在儿童癫痫治疗中的血药浓度监测情况,以利指导合理用药。
6) antiepileptics
抗癫痫药
1.
Advance in research of fetal malformations induced by antiepileptics;
抗癫痫药致胎儿畸形的研究进展
2.
Effect of hemolysis in antiepileptics plasma sample determined by FPIA;
溶血现象对抗癫痫药血药浓度测定的影响
补充资料：抗癫痫药血清浓度监测
抗癫痫药血清浓度监测
monitoring of serum concentration of antiepileptic drugs
通过血清中抗癫痫药物浓度的测定来指导癫痫治疗的一种方法。常用的有分光光度计法、薄层层析法、气相层析-色谱法、气-液层析法、高压液相层析法、放射免疫分析法、酶多相免疫测定法等。以气-液层析法应用最广，酶多相免疫测定法最精确。目前可对苯妥英钠、苯巴比妥、丙戊酸钠、卡马西平、扑痫酮和安定类药物等进行测定。监测指征：①抗癫痫药超量仍不能控制发作；②剂量和血浓度间不协调；③出现中毒症状；④发作尚未控制而又无法判断是剂量不足或过量；⑤服用安全范围小的药物；⑥多种药物联合应用；⑦科研或对比疗效。药物血清浓度监测需达稳态后进行，主要用于指导合理用药，监测和提高疗效，减少用药量及毒副作用。
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参考词条