The pH sensitive chitosan solution was neutralized to physiological pH by glycerol phosphate and remained stable at room temperature while allowing gel formation upon heating to 37 ℃.

Feasibility Study on the Repair of Articular Cartilage Defects with the Injectable Chitosan/glycerophosphate Compound Mesenchymal Stem Cells in Swines;

In this paper,thermo-sensitive gelling systems based on a carboxymethyl chitosan/glycerophosphate salt(CMCS/GP) complex were prepared.

Thermo-sensitive neutral systems based on a chitosan/glycerophosphate salt complex were prepared.

Objective To evaluate the feasibility of the injectable thermosetting chitosan and glycerophosphate(C/GP) gel as tissue engineering scaffold by observing its biocompatibility and survival ability of BMCs encapsulated in the gel.

Objective To investigate the feasibility and the effectiveness of allograft chondrocytes mixed in the injectable thermosetting chitosan and glycerophosphate(C-GP) gel forming hyaline cartilage in vivo and repairing the whole layer defects of femur trochlea of rabbit keen joint.

Chitosan/glycerophosphate (CS/GP) hydrogel, a novel thermosensitive hydrogel, is an important system due to its sol-gel transition at body temperature.