One-pot synthesis of 3,4-dihydropyrimidin-2-(1H)-ones catalyzed by copper o-toluenesulfonate

Gem-diacetates were synthesized from corresponding aromatic or aliphatic aldehydes and acetic anhydride catalysed by acetic acid-assisted copper o-toluenesulfonate as synergistic catalysts at room temperature under solvent-free conditions.

Tetrahydropyranyl ethers were synthesized from corresponding alcohols or phenols and 3,4-dihydro-2H-pyran using acetic acid assisted copper o-toluenesulfonate as a synergistic catalyst at room temperature under a solvent-free condition.

Separation of L-leucine from pig blood hydrolysate using precipitation method by reacting with 3,4-dimethyl-benzenesulfonic acid;