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1)  Verapamil [英][,virə'pæmil]  [美][və'ræpə,mɪl]
戊脉胺
2)  α-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]methyl-lamino]propyl]-3,4-dimethoxy-α-(1-methylethyl)benzeneacetonitrile
戊脉胺
3)  Pentylamine [,pentil'æmi:n]
戊胺
4)  1-Aminopentane
戊胺
5)  sulfadicrolamide
磺胺戊烯胺
6)  cyclopentylamine
环戊胺
1.
The raw material adipic acid was dehydrated and decarboxylated with Ba(OH)_2 to prepare cyclopentanone at first,and then cyclopentanone was reacted with ammonia in hydrogen to give the final product cyclopentylamine.
环戊胺是重要的有机化工原料和中间体,广泛用于医药、农药等的合成。
2.
On the basis of consulting a large amount of literatures and comparing the different routes synthesizing cyclopentylamine, a new cyclopentylamine synthesis route was presented in the paper, namely, the raw material adipic acid was dehydrated and decarboxylated with Ba(OH)2 to prepare cyclopentanone at first step, and in turn the cyclopentanone obtained was reacted with.
环戊胺是重要的有机化工原料和中间体,用于医药、农药等的合成。
补充资料:戊脉胺
分子式:C27H38N2O4
分子量:454.59
CAS号:52-53-9

性质:粘稠的淡黄色油状液体。沸点243-246℃(1.3Pa),折光率(nD25)1.5448。溶于苯、醚,易溶于低级醇、丙酮、乙酸乙酯、氯仿,难溶于已烷,不溶于水。其盐酸盐([152-11-4])为白色至类白色结晶性粉末。熔点138.5-140.5℃(分解)。易溶于甲醇、二甲基甲酰胺,溶于乙醇、异丙醇、丙酮、乙酸乙酯,不溶于氯仿。无臭,味苦。

制备方法:二甲氧基苯乙腈与溴异丙烷进行烃化反应后,与1,3-氯溴丙烷进行氯丙基化反应,然后与3,4-二甲氧基苯乙胺缩合制成维拉帕米。

用途:选择性冠脉扩张剂。主要用于阵发性室外上性心动过速,对心房纤颤或心房扑动仅能减慢心室率,仅有少数转为窦性心率,也用于心绞痛、高血压和肥厚型梗塞性心肌病。

说明:补充资料仅用于学习参考,请勿用于其它任何用途。
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