1) androgen response element
雄激素效应元件
1.
[Methods] The oligonucleotides of the mouse mammary tumor viruslong terminal repeat (MMTV-LTR) containing androgen response element (ARE) and promoter were cloned into the kpn Ⅰ and Bgl Ⅱ sites of pCAT3-basic, creating pMMTV-CAT.
[方法]合成含雄激素效应元件(ARE)和启动子的小鼠乳腺癌病毒长末端重复序列(MMTV-LTR),定向插入报告基因质粒pCAT3-basic的Kpn Ⅰ和Bgl Ⅱ之间,构建受ARE调控的CAT报告基因质粒pMMTV-CAT,将表达AR的质粒AR/pcDNA3。
2) Androgen responsive element
雄激素应答元件
1.
Androgen responsive element decoy DNA inhibits the promoter of prostate specific antigen and induces apoptosis of LNCaP cells;
雄激素应答元件陷阱DNA抑制PSA基因启动子的作用并诱导LNCaP细胞凋亡(英文)
2.
To observe the effect of exogenous androgen responsive element decoy on the promoter of prostate specific antigen (PSA), pGL3 PSA luciferase expression vector containing 640 bp DNA fragment of the PSA gene 5′ promoter region was constructed.
研究雄激素应答元件假冒DNA(AREdecoy)对前列腺特异抗原 (PSA)基因启动子的抑制作用 。
3) androgen receptor response element
雄激素受体反应元件
4) estrogen responsive element
雌激素效应元件
1.
Preliminary studies have been made on the effect of bound water on the binding of estrogen receptor with estrogen responsive element in vitro.
本文以雌激素受体(ER)同32bp雌激素效应元件(ERE)体外结合为模型,对结合水分子的参与进行探索性研究。
5) estrogen response element
雌激素效应元件
1.
It was shown that the translational product could bind to the estrogen response element(ERE).
利用体外翻译系统,翻译了能与雌激素效应元件(ERE)结合的全长的人雌激素受体(hER)。
6) anti-androgen effect
抗雄激素效应
1.
Conclusion:DEHP could cause dysfunction of the testis gubernaculum via its anti-androgen effect,induce cryptorchidism,and cause dysplasia and dysfunction of Sertoli cells,Leydig cells and spermatogenic cells in fetal mice.
结论:DEHP可通过抗雄激素效应导致睾丸引带功能障碍,使睾丸下降发生异常而诱导小鼠隐睾;同时造成睾丸Ser-toli细胞、睾丸Leydig细胞和生精细胞的发育障碍和功能改变。
补充资料:激素效应元件
激素效应元件(her):指内固醇甲状腺素等激素受体结合的一段短的dna序列(12~20bp),这类受体结合dna后可改变相邻基因的表达。
说明:补充资料仅用于学习参考,请勿用于其它任何用途。
参考词条