1) α-C alkyl homologues of octanoyl acetal
辛酰乙醛α-C烃基修饰物
1.
Based on the structure of octanoyl acetal, threeα-C alkyl homologues of octanoyl acetal sodium sulfite (HOU-C_8C_n) including 2-octanoyl-1-hydroxy propyl sulfonate (HOU-C_8C_1)、2-octanoyl-1-hydroxy butyl sulfonate (HOU-C_8C_2)、2-octanoyl-1-hydroxy hexyl sulfonate (HOU-C_8C_4) had been synthesized successfully in our laboratory by modification theα-C of HOU-C_8.
本课题以辛酰乙醛为模板，在其活性最强的部位α-C上引入了不同碳链长度的烷基，验证性地合成了三种辛酰乙醛α-C烃基修饰物(HOU-C_8C_n)：2-辛酰丙醛亚硫酸钠(HOU-C_8C_1)、2-辛酰丁醛亚硫酸钠(HOU-C_8C_2)和2-辛酰己醛亚硫酸钠(HOU-C_8C_4))，初步研究了它们的体外抗菌作用，并以亲脂性不同和电荷密度不同为线索，分析了它们在体外抗菌活性的异同。
2) α-C octanoyl acetal sodium sulfite derivatives
辛酰乙醛α-碳衍生物
3) aldhyde modification
醛基修饰
4) poly(oxy-1,2-ethanediyl), alpha-[2-[ethyl[(heptadecafluorooctyl)sulfonyl]amino]
α-[2-[乙基[(十七氟辛基)磺酰]氨基]乙基]-&omega
5) acetylation
[ə,seti'leiʃən]
乙酰化修饰
1.
Constructions of Gcn5 shRNAs interfere the histone acetylation modification with stem cell differentiation;
Gcn5基因shRNA的载体构建及其对干细胞分化中组蛋白乙酰化修饰的干扰作用
2.
Objective To construct 7 shRNA plasmids targeted to Gcn5 and to explore their role on histone acetylation in regulating MSCs differentiation into cardiomyocytes.
目的通过组蛋白乙酰化作用相关shRNA质粒转染5氮杂胞苷(5-azacytid ine,5-aza)诱导后不同时间段间充质干细胞心肌发育基因的检测,探讨乙酰化修饰在干细胞特化心肌样细胞转录调控中的作用。
3.
As acetylation of proteins facilitates the expression of proapoptotic genes and induces the degradation of oncoproteins and antiapoptotic proteins, HDACi induce apoptosis by activating the apoptotic signal transduction pathways at transcription and posttranslation levels.
组蛋白去乙酰化酶抑制剂(HDACi)是一类新的化疗药物,能够有效抑制组蛋白去乙酰化酶的活性,促进组蛋白及非组蛋白的乙酰化修饰,在转录和翻译后修饰水平调控肿瘤靶蛋白及凋亡相关蛋白的表达和降解,活化凋亡信号通路,诱导肿瘤细胞凋亡。
6) 4-ethyl-Octanal
4-乙基辛醛
补充资料：α-辛基-&omega
CAS：27252-75-1
分子式：(C2H4O)nC8H18O
沸点：165-200℃
中文名称：α-辛基-ω-羟基-聚(氧乙烯)
英文名称：.alpha.-octyl-.omega.-hydroxy-Poly(oxy-1,2-ethanediyl)
Octyl alcohol, ethoxylated
分子式：(C2H4O)nC8H18O
沸点：165-200℃
中文名称：α-辛基-ω-羟基-聚(氧乙烯)
英文名称：.alpha.-octyl-.omega.-hydroxy-Poly(oxy-1,2-ethanediyl)
Octyl alcohol, ethoxylated
说明：补充资料仅用于学习参考，请勿用于其它任何用途。
参考词条