2) Subendocardial myocardium
心内膜下心肌
1.
Objective This study was performed to observe the effect of microvascular density,and the expression of MMP-2/TIMP-2 in the subendocardial myocardium of DOCA-salt Hypertensive Rats(DHR) left ventricle under the intervention of bosentan,and to evaluate the signifance of expression of MMP-2/TIMP-2 and the role of endothelin-1 on the expression of MMP-2/TIMP-2 in DHR heart.
结果在DHR左心室心内膜下心肌中存在微小动脉密度增加和毛细血管密度减少,MMP-2的mRNA和MMP-2/TIMP-2的蛋白表达上调;波生坦能抑制血压升高,减轻微小血管损害,下调MMP-2/TIMP-2的mRNA和蛋白表达,MMP-2的表达同微小血管密度间具有良好的相关性。
3) myocardial ischemia
心肌缺血
1.
Protective effect of captopril on acute myocardial ischemia in rats;
卡托普利对大鼠心肌缺血损伤的保护作用
2.
Temporal phenomenon of myocardial ischemia and aerobic exercises-induced VEGF expression: an experimental study;
心肌缺血和有氧运动训练诱导VEGF表达时间规律的实验研究
3.
Effects of Yiqihuoxuejiedu Decoction on Blood Nitrogen Monoxidum,Endothelin and Muscle Serum Malonaldehyde in Rabbits with Acute Myocardial Ischemia;
益气活血解毒汤对实验性家兔急性心肌缺血一氧化氮、内皮素和丙二醛的影响
4) myocardium ischemia
心肌缺血
1.
Study on Guanxin salvia drop pill to pituitary induced acute myocardium ischemia;
冠心丹参滴丸抗垂体后叶素致大鼠急性心肌缺血的研究
2.
Objective:To observe the effect of Xinguanxinsuhe Drop Pill(XDP)Ⅰ、Ⅱ and Guanxinsuhe capsule on isoprenaline(ISO)-induced acute myocardium ischemia.
目的:观察新冠心苏合滴丸Ⅰ号、Ⅱ号、冠心苏合胶囊3药对异丙肾上腺素(ISO)所致大鼠急性心肌缺血的保护作用。
3.
Objective To investigate the relationship of performed percutaneous transluminal coronary angioplasty(PTCA) and/or stenting myocardium ischemia and their symptoms and arrhythmia in the elderly patients with coronary artery disease(CAD).
目的探讨老年冠心病患者经皮腔内冠状动脉成形术(PTCA)及支架置入术后心肌缺血与临床症状及心律失常的关系。
5) myocardial ischemic
心肌缺血
1.
Objective:To observe the effects of electroacupuncture on expression of HSP90 of myocardial ischemic area in rabbit heart.
目的:观察电针刺激对急性心肌缺血家兔心肌热休克蛋白90(HSP90)表达的影响。
2.
Objective:Electroacupuncture at Neiguan,Daling and Ximen of Hand Jueyin meridian and observe the effects of electroacupuncture of expression of vascular endothelium growth factor(VEGF)of myocardial ischemic area in rabbit heart.
目的:采用免疫组化和分子原位杂交方法,观察电针针刺双侧“大陵”、“内关”、“郄门”穴后,缺血心肌VEGF及VEGFmRNA的表达,探讨针刺改善急性心肌缺血及心包经穴与心脏相关联系的机制。
3.
Objective To improve the successful rate of operation and the livability in establishing acute myocardial ischemic rat model.
目的改进大鼠急性心肌缺血动物实验模型时,提高手术的成功率和动物成活率。
6) ischemic myocardium
缺血心肌
1.
Purpose To study the expression of the hypoxia inducible factor-1α(HIF-1α) and its downstream gene vascular endothelial growth factor(VEGF) on ischemic myocardium after acute myocardiac infarction(AMI) in different time points,so as to provide guidance in clinical application of adenovirus mediated HIF-1α gene(Ad-HIF-1α).
目的研究腺病毒介导的低氧诱导因子-1α(HIF-1α)及其下游基因血管内皮生长因子(VEGF)在急性心肌梗死(AMI)后的缺血心肌不同时间点的表达,为临床应用HIF-1α转基因治疗心肌缺血提供实验依据。
2.
To study the expression about HIF-1α mRNA in ischemic myocardium after acute myocardiac infarction(AMI), the animal AMI model were made by rabbits, divided into 4 groups at random and infected Ad-HIF-1α,Ad-Blank,Rz-HIF-1α respectively,Sham group was regarded as control.
研究腺病毒介导的低氧诱导因子-1α(HIF-1α)在急性心肌梗死(AMI)后缺血心肌中的表达变化。
3.
Objective To observe the morphological change of nucleus of ischemic myocardium.
目的 观察缺血心肌细胞核的形态改变。
补充资料:抗心肌缺血药
分子式:
CAS号:
性质:又称抗心肌缺血药。是一类防治心绞痛的药物。抗心绞痛药可通过舒张冠状动脉,解除其痉挛或促进侧枝循环形成增加冠状动脉供血或通过舒张静脉或外周小动脉,减轻心脏前后负荷、减慢心率、降低心肌收缩性而降低心肌对氧的需求发挥抗心绞痛作用。常用药物有硝酸甘油、硝酸异山梨酯、普萘洛尔、美托洛尔、硝苯地平、维拉帕米等。
CAS号:
性质:又称抗心肌缺血药。是一类防治心绞痛的药物。抗心绞痛药可通过舒张冠状动脉,解除其痉挛或促进侧枝循环形成增加冠状动脉供血或通过舒张静脉或外周小动脉,减轻心脏前后负荷、减慢心率、降低心肌收缩性而降低心肌对氧的需求发挥抗心绞痛作用。常用药物有硝酸甘油、硝酸异山梨酯、普萘洛尔、美托洛尔、硝苯地平、维拉帕米等。
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参考词条